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What is the prevalence of Aquagenic Syringeal Acrokeratoderma?

How many people does Aquagenic Syringeal Acrokeratoderma affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Aquagenic Syringeal Acrokeratoderma

Aquagenic syringeal acrokeratoderma is a rare condition characterized by transient wrinkling and whitening of the palms and soles upon contact with water. It predominantly affects young females, with only a few cases reported in males. The exact prevalence of this condition is unknown, as it is often underdiagnosed or misdiagnosed. However, it is considered to be a very rare disorder. Aquagenic syringeal acrokeratoderma is not associated with any significant medical complications and typically does not require treatment. Further research is needed to determine the exact prevalence and underlying mechanisms of this condition.

Aquagenic syringeal acrokeratoderma is a rare skin condition characterized by the development of transient white papules or plaques on the palms and soles after exposure to water. Although the exact prevalence of this condition is not well-established, it is considered to be extremely rare.


Due to its rarity, there is limited information available regarding the prevalence of aquagenic syringeal acrokeratoderma. However, it has been reported in both males and females, typically appearing during adolescence or early adulthood. The condition is not believed to be hereditary and does not seem to be associated with any underlying systemic diseases.


While the exact cause of aquagenic syringeal acrokeratoderma remains unknown, it is thought to be related to an abnormal reaction of the skin to water, possibly due to altered sweat gland function. The condition is typically benign and does not cause any significant symptoms or complications.


As aquagenic syringeal acrokeratoderma is a rare condition, further research is needed to determine its true prevalence and better understand its underlying mechanisms.


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