Megalocornea Intellectual Disability Syndrome synonyms
What other names are the Megalocornea Intellectual Disability Syndrome known by? Synonyms and other terms with which Megalocornea Intellectual Disability Syndrome is known.
Megalocornea Intellectual Disability Syndrome, also known as MICDS, is a rare genetic disorder characterized by the presence of abnormally large corneas and intellectual disability. This condition primarily affects males, and its exact prevalence is unknown.
Synonyms:
- MICDS
- Megalocornea syndrome
- Megalocornea-intellectual disability syndrome
- Megalocornea and intellectual disability syndrome
- Intellectual disability with megalocornea
Individuals with MICDS typically have significantly larger corneas than normal, which can lead to vision problems such as nearsightedness or astigmatism. The intellectual disability associated with this syndrome can range from mild to severe, affecting cognitive abilities, learning, and adaptive skills.
Other common features of MICDS may include facial dysmorphism (distinctive facial features), such as a broad forehead, deep-set eyes, a flat nasal bridge, and a wide mouth. Some affected individuals may also exhibit joint hypermobility, which allows for an increased range of joint movement.
Due to the rarity of MICDS, there is limited information available regarding its underlying genetic cause. However, it is believed to be inherited in an X-linked recessive manner, meaning the gene mutation responsible for the condition is located on the X chromosome.
Management of MICDS involves a multidisciplinary approach, including regular eye examinations to monitor and address vision problems, early intervention programs to support developmental delays, and educational interventions tailored to the individual's specific needs.
In summary, Megalocornea Intellectual Disability Syndrome (MICDS) is a rare genetic disorder characterized by abnormally large corneas and intellectual disability. It primarily affects males and can present with additional features such as facial dysmorphism and joint hypermobility. MICDS is managed through a multidisciplinary approach, addressing vision problems and providing appropriate support and interventions for intellectual disability.
