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What is the history of Alkaptonuria?
When was Alkaptonuria discovered? What is the story of this discovery? Was it coincidence or not?
Alkaptonuria was one of the four diseases described by Sir Archibald Edward Garrod, as being the result of the accumulation of intermediates due to metabolic deficiencies. He linked ochronosis with the accumulation of alkaptans in 1902 and his views on the subject, including its mode of heritance, were summarized in a 1908 Croonian Lecture at the Royal College of Physicians.
Copied from Wikipedia
https://en.m.wikipedia.org/wiki/Alkaptonuria
Copied from Wikipedia
https://en.m.wikipedia.org/wiki/Alkaptonuria
Posted Jun 15, 2017 by Shane 2255
Alcapton was Used to describe a persons urinary compound in 1897, later identified as Homogentisic acid, by 1908 Archibald Garrod has suggested that Alkaptonuria was an inborn error of metabolism. Because it was a very rare nothing has actually been done about this"black bone"/ black urine disease.
Posted Sep 27, 2017 by Sandra 2000
Translated from spanish
Improve translation
It was the first rare disease or rare discovered by Archibald Garrod in 1902
Posted May 18, 2017 by Marcelah38 2365
