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Is Antisynthetase syndrome hereditary?

Here you can see if Antisynthetase syndrome can be hereditary. Do you have any genetic components? Does any member of your family have Antisynthetase syndrome or may be more predisposed to developing the condition?

Is Antisynthetase syndrome hereditary?
2 answers
Myself and my two sons have had skin issues our whole lives. Sometimes severe but mostly just troublesome. My younger son has been diagnosed with ASS. He was diagnosed with "mechanics hands" 25yrs ago but no one looked any deeper to find out how he had this. He was diagnosed after he had develpoed pulmonary fibrosis.

Posted Nov 3, 2020 by Cathleen 100
I was able to track my antisynthetase syndrome back to exposure to coating sprays which I worked with. The silica nanoparticles in them gradually shut down both my muscle function and respiratory function by interfering with energy production at a cellular level. Without sufficient oxygen to operate normally my cells produced an enzyme called threonyl tRNA synthetase in order to trigger development of new blood vessels in hope that it would draw more oxygen to the cells. As my body recognised that this wasn't possible it produces the PL-7 autoimmune antibodies, associated with my own antisynthetase syndrome, in order to destroy the threonyl tRNA synthetase to try to prevent it from forming the blood vessels, which can be associated with cancer. While my own case was related to toxic exposure the condition can be completely genetic in origin, it just depends on all of the factors involved. Even though it could be genetic it doesn't mean that something can't be done about it as medical researchers are studying how some forms of genetic mutations, which result in this kind of thing, can actually be reversed to what they term the 'wild type' gene, associated with good health.

Posted Apr 2, 2022 by Barry 100

Is Antisynthetase syndrome hereditary?

Antisynthetase syndrome life expectancy

What is the life expectancy of someone with Antisynthetase syndrome?

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Celebrities with Antisynthetase syndrome

Celebrities with Antisynthetase syndrome

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Is Antisynthetase syndrome contagious?

Is Antisynthetase syndrome contagious?

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ICD9 and ICD10 codes of Antisynthetase syndrome

ICD10 code of Antisynthetase syndrome and ICD9 code

1 answer
Natural treatment of Antisynthetase syndrome

Is there any natural treatment for Antisynthetase syndrome?

1 answer
Living with Antisynthetase syndrome

Living with Antisynthetase syndrome. How to live with Antisynthetase syndro...

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Antisynthetase syndrome diet

Antisynthetase syndrome diet. Is there a diet which improves the quality of...

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History of Antisynthetase syndrome

What is the history of Antisynthetase syndrome?

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World map of Antisynthetase syndrome

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Stories of Antisynthetase syndrome

ANTISYNTHETASE SYNDROME STORIES

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Antisynthetase syndrome forum

ANTISYNTHETASE SYNDROME FORUM

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