The available literature on the history of the ulcerative colitis is scarce. This disease was described for the first time in the year 640.C. The first texts written by authors such as Aretaeus and Soranus described several forms of diarrhea is not contagious.Subsequently, to 1745, some sources claimed that prince Charles
Edward Stuart, pretender jacobite to the throne of Great Britain as “Charles III of England and Scotland” had suffered an episode of diarrhea that improved with a diet without milk and probably would for a flare of ulcerative Colitis.It was not until 1859 that the disease was named as ulcerative colitis for the first time by Dr Samuel Wilks described a case of a patient with ulcerative colitis, so the discovery of the disease has been associated with his name. The article written by Dr. Wilks was actually a letter to “The Times” and Gaceta Médica that contained the description of an autopsy that Dr. Wilks had been a young girl, Isabella, who had died after weeks of bloody diarrhea. In the letter, it was stated that despite the fact that the woman had suffered an episode of diarrhea for a cause a non-infectious, had died as a result of taking a poison to cause the abortion.