Pain that is described as deep, aching, cold, burning, and/or increased skin sensitivity
An initiating injury or traumatic event, such as a sprain, fracture, minor surgery, etc., that should not cause as severe pain as being experienced or where the pain does not subside with healing
Pain (moderate-to-severe) associated with allodynia, that is, pain from something that should not cause pain, such as the touch of clothing or a shower
Continuing pain (moderate-to-severe) associated with hyperalgesia, that is, heightened sensitivity to painful stimulation)
Abnormal swelling in the affected area
Abnormal hair or nail growth
Abnormal skin color changes
Abnormal skin temperature, that is, one side of the body is warmer or colder than the other by more than 1°C
Abnormal sweating of the affected area
Limited range of motion, weakness, or other motor disorders such as paralysis or dystonia
Symptoms and signs can wax and wane
Can affect anyone, but is more common in women, with a recent increase in the number of children and adolescents who are diagnosed