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Since there is no cure for AS, some medications help to ease the symptoms (like biologics and Nonsteroidal anti-inflammatory drugs or NSAIDs, see http://www.mayoclinic.org/diseases-conditions/ankylosing-spondylitis/diagnosis-treatment/treatment/txc-20261171), but in a lot of cases other treatments help great deal, too: physical therapy, food supplements (natural anti-inflammatory pills like curcumin or boswellia; omega 3; vitamin D3; etc.), anti-inflammatory diets (low to no starch, gluten, sugar; more protein & fermented food). A lot of movement and meditation goes a long way, too. Mind you, these natural, less invasive treatments are not a cure for the disease, they ease the symptoms and are only efficient in the long run!