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To begin with Physical therapy and occupational therapy is great. Water therapy was the best of them all. It helps with mobility and strengthening. Accupunctire and massage works well for some too and light exercise and yoga. Movement is the key to AS . when all other treatments fails there are medications such as biologics, Methotrexate, Plaquinel, Sulfanazine, pain meds and some antidepressants that help to relieve pain as well as slow the progression of the disease. There is no cure but more treatment options are becoming available.