Original
Prednisone or other steroids are helpful short-term to help reduce the inflammation from Behcet's. As I tapered off of prednisone I began imuran, which my rhuematologist believed was preferred for a longer term basis. Colchicine has been reported to have some benefits for oral lesions in some patients, although I did not find it very effective for me. Both prednisone and Imuran have generally been very effective in reducing my more serious symptoms (i.e. uveitis/eye lesions), and while I have experienced some break-through flare-ups in other lesions (i.e. oral and skin) I feel that they have generally allowed me to live a pretty functional life.