Original
My most debilitating is dysautonomia and orthostatic hypotension from classical with weak veins. My daughter had a major brain hemmorrage less than a year ago because of eds 2 or 3, we are currently gene tested for an unknown mutation of type 2 but still diagnosed 3 because it is unknown. For my children and I, weak veins (from whatever type) that cause labile vitals and might take our lives would be what I would change.