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A tailor made cortisol routine for each individual. No one person being the same, this is important for assessment of the level of 'replacement' your body needs.
There are many medicines available. Most people take anywhere from 1-3 doses split throughout the day, decreasing in level as the day progresses. Highest dose being in the morning (the body naturally produces in the early morning) & lowest dose being in the late afternoon/early evening to reduce levels ready for sleep.