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If your condition is well controlled with medication and diet, a person's life expectancy can be the same as any other.
Complications that could endanger your life would be a blood clot. Every one who I've met that has Factor V Leiden has had to realize that yes, this mutation can kill you. Even worse, so can your medication. Having regular blood testing can help control your medication (warfarin) levels. Blood thinners will make you more susceptible to major bleeds. Which can be life threatening.
Progress has been made with new innovations for the IVC filter. New and safer designs help prevent clots from traveling to your heart, lungs, and brain. New medications are always coming out as well.