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Factor VII deficiency may be either inherited or acquired. The inherited version is quite rare. Fewer than 200 documented cases have been reported. Both of your parents must carry the gene in order for you to be affected.
Acquired factor VII deficiency, in contrast, occurs after birth. It can occur as a result of medications or diseases that interfere with your Factor VII. Drugs that can impair or reduce Factor VII function include:
- antibiotics
- blood thinners, such as warfarin
- some cancer drugs, such as interleukin-2 therapy
- antithymocyte globulin therapy used to treat aplastic anemia