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Malignant Hypothermia is diagnosed by doing a biopsy on your right leg or prominent leg. The doctor would set up an appointment with the hospital to do the biopsy. On this day they would treat you as if you had Malignant Hypothermia and all precautions are in order. During surgery the doctor will slice a one inch cut through your skin. Then he or she will take a sample of one inch each of every muscle in that leg. They will send the samples off to Boston, Massachusetts. Where each muscle will be tested in its on certain way for Malignant Hypothermia. I have heard now they have a another caffeine test they can do now also that doesn't involve surgery. But surgery is the best.