Depression is part and parcel of the Acute Porphyrias. It is one of the symptoms. It can be very difficult to deal with and one needs to look at ways to manage the individual person.
A medical doctor may often prescribe safe drugs to deal with depression.
The level of depression will affect everyone differently. Its important to have a support system in place, partake in activities that bring out your creative side, these can all have a positive effect on ones mood. Remember that tomorrow is another day, you are having a bad day today and thats ok. The important thing to realise when the depression becomes lingering or you are in a bad place that you need to seek help!