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Infertility and then a lab might check your sperm count, if it comes out zero, then a DNA study will probably be done. When my sperm count came out zero in 1980 no recommendations were given to have a DNA study done. One is usually already seeing an Endocrinologist at this point but if not then it is best to go see an Endo Doctor who will then order a DNA study. Other signs and symptoms could be looking 14 yo at 40, though that is only related to the XXY type not the XYY type. Not having a physical appearance deviation has led to the large numbers of males with this condition not being diagnosed. Within the Socialized Medicine countries most if not all newborns are DNA tested. That is where the increase in testing of this condition is being done.