克利佩尔-费尔综合征(KFS)是否可以遗传?

您可在这里查看克利佩尔-费尔综合征(KFS)是否可以遗传。您是否有相关的基因因素?您是否有家人是克利佩尔-费尔综合征(KFS)患者,他们有什么患病的风险因素?

原本


When Klippel-Feil Syndrome is caused by mutations in the GDF6 or GDF3 genes, it is inherited in an autosomal dominate pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder.

When caused by mutations in the MEOX1 gene, Klippel-Feil Syndrome is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.

As a feature of another disorder, Klippel-Feil Syndrome is inherited in whatever pattern the other disorder follows.

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