Acute myelogenous leukemia (AML) synonyms

Acute myelogenous leukemia (AML) is primarily known as acute myeloid leukemia, though it is frequently referred to as acute non-lymphocytic leukemia (ANLL) in older clinical records. These terms all describe a group of aggressive cancers characterized by the rapid growth of abnormal white blood cells that build up in the bone marrow and blood, interfering with normal blood cell production.

Why does Acute myelogenous leukemia (AML) have multiple names?

The nomenclature for Acute myelogenous leukemia (AML) has evolved alongside our understanding of hematology. Historically, clinicians used terms like "acute granulocytic leukemia" or "acute myeloblastic leukemia" to describe the specific cell lines involved. The transition to the term "acute myeloid leukemia" reflects a more modern, standardized approach to classification that encompasses various subtypes categorized by the World Health Organization (WHO).

What are the common synonyms and historical terms for AML?

When reviewing medical records or older research literature, you may encounter several variations of the name. Understanding these synonyms is vital for patients navigating their diagnosis:

• Acute myeloid leukemia: The currently preferred term by hematologists and oncologists.


• Acute non-lymphocytic leukemia (ANLL): A common historical term used to distinguish Acute myelogenous leukemia (AML) from acute lymphoblastic leukemia (ALL).


• Acute myeloblastic leukemia: Often used when the disease is primarily characterized by the proliferation of myeloblasts.


• Acute granulocytic leukemia: An older term referring to the lineage of granular white blood cells.

How is Acute myelogenous leukemia (AML) officially classified?

Major medical databases provide standardized identifiers to ensure consistency in research and clinical care for Acute myelogenous leukemia (AML). In the ICD-10/11 classification systems, it is generally coded under C92.0. The Orphanet identifier for Acute myelogenous leukemia (AML) is ORPHA:519, while the OMIM database tracks the genetic variants associated with the condition under various entries, such as #601626.

Which name should patients and providers use?

While "Acute myelogenous leukemia" and "Acute myeloid leukemia" are used interchangeably in clinical practice, "Acute myeloid leukemia" is the most widely accepted term in contemporary medical literature. Currently, 62 members of the DiseaseMaps.org community are managing their journey with Acute myelogenous leukemia (AML), using these terms to share experiences and access resources.

Next steps

• Confirm your specific subtype of Acute myelogenous leukemia (AML) with your hematologist, as this influences treatment protocols.


• Utilize the term "Acute myeloid leukemia" when searching for clinical trials on platforms like ClinicalTrials.gov.


• Join the DiseaseMaps.org community to connect with others who have navigated the diagnostic process for this condition.

Medical disclaimer: This content is for informational purposes only and does not constitute medical advice; always consult with a qualified healthcare professional regarding your diagnosis and treatment.

References

• Orphanet: Acute myeloid leukemia (ORPHA:519)


• NIH GARD: Acute myeloid leukemia (GARD: 6516)


• OMIM: Leukemia, Acute Myeloid (OMIM: 601626)


• National Cancer Institute (NCI): Adult Acute Myeloid Leukemia Treatment (PDQ)