Short answer · Medically reviewed summary · Last updated: 2026-05-08

The primary ICD-10 code for Adrenal Insufficiency is E27.4, while the corresponding ICD-9 code is 255.4. These codes are essential for medical billing and clinical documentation to ensure patients with Adrenal Insufficiency receive appropriate coverage and care. What are the different classifications of Adrenal Insufficiency? Medical providers distinguish between primary, secondary, and tertiary forms of Adrenal Insufficiency.

2 people with Adrenal Insufficiency have shared their first-person experience on this question at DiseaseMaps.

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ICD10 code of Adrenal Insufficiency and ICD9 code

ICD-10 and ICD-9 codes for Adrenal Insufficiency, with classification details for clinicians, coders and patients.

ICD9 and ICD10 codes of Adrenal Insufficiency

The primary ICD-10 code for Adrenal Insufficiency is E27.4, while the corresponding ICD-9 code is 255.4. These codes are essential for medical billing and clinical documentation to ensure patients with Adrenal Insufficiency receive appropriate coverage and care.



What are the different classifications of Adrenal Insufficiency?


Medical providers distinguish between primary, secondary, and tertiary forms of Adrenal Insufficiency. Primary Adrenal Insufficiency, often known as Addison’s disease, occurs when the adrenal glands themselves are damaged. Secondary Adrenal Insufficiency results from a lack of adrenocorticotropic hormone (ACTH) production by the pituitary gland. Understanding the specific type of Adrenal Insufficiency is vital for determining the correct hormone replacement therapy protocol.



How is Adrenal Insufficiency coded in medical records?


While E27.4 is the general code for other and unspecified adrenocortical insufficiency, clinicians may use more specific codes depending on the underlying cause of your Adrenal Insufficiency:



  • E27.1: Primary adrenocortical insufficiency (Addison's disease).

  • E27.3: Drug-induced adrenocortical insufficiency.

  • E27.40: Unspecified adrenocortical insufficiency.

  • 255.41: Glucocorticoid deficiency (ICD-9 specific).



Why is accurate diagnosis important for Adrenal Insufficiency?


Adrenal Insufficiency is a life-altering condition that requires lifelong hormone replacement. With 113 community members on DiseaseMaps.org sharing their journeys, we know that timely diagnosis is crucial to prevent an adrenal crisis, a medical emergency caused by severe cortisol deficiency. Proper coding for Adrenal Insufficiency ensures that patients have consistent access to life-saving medications like hydrocortisone or fludrocortisone.



Next steps



  • Review your medical records to confirm that your specific form of Adrenal Insufficiency is coded accurately to facilitate insurance coverage for medications.

  • Consult an endocrinologist to ensure your management plan for Adrenal Insufficiency is current.

  • Join the 113 members in the DiseaseMaps community to share experiences and coping strategies for living with Adrenal Insufficiency.

  • Always carry an emergency medical identification card stating your Adrenal Insufficiency diagnosis.



Medical disclaimer: This information is for educational purposes only and should not replace professional medical advice, diagnosis, or treatment.



References



  • NIH Genetic and Rare Diseases Information Center (GARD): Adrenal Insufficiency Overview.

  • Orphanet: Rare endocrine diseases database (ORPHA:96147).

  • ICD-10 Data: E27.4 Other and unspecified adrenocortical insufficiency.

  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): Adrenal Insufficiency and Addison's Disease.

Author: DiseaseMaps Editorial Team
Reviewed against authoritative medical sources (NIH GARD, Orphanet, OMIM)
Last updated: 2026-05-08
Sources cited: NIH Genetic and Rare Diseases Information Center (GARD): Adrenal Insufficiency Overview. · Orphanet: Rare endocrine diseases database (ORPHA:96147). · ICD-10 Data: E27.4 Other and unspecified adrenocortical insufficiency. · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): Adrenal Insufficiency and Addison's Disease.
Medical disclaimer: This information does not substitute professional medical advice. Always consult your doctor before making health decisions.
Source: DiseaseMaps.org
3 answers
ICD9 255.4 to 255.9
ICD10 secondary E23
primary E27

Posted Jan 9, 2018 by Linda 1520
255 or 27 depending on exact diagnosis.

Posted Jan 29, 2024 by AdrienneSmith 1600

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