Short answer · Medically reviewed summary · Last updated: 2026-04-07

The ICD-10 code for Ankylosing Spondylitis is M45, while the older ICD-9 classification is 720.0. These codes are essential for medical documentation, insurance billing, and tracking the prevalence of Ankylosing Spondylitis within healthcare systems worldwide. What is the clinical significance of the Ankylosing Spondylitis classification? Ankylosing Spondylitis is a chronic, systemic inflammatory rheumatic disease that primarily affects the axial skeleton, specifically the sacroiliac joints and the spine.

9 people with Ankylosing Spondylitis have shared their first-person experience on this question at DiseaseMaps.

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ICD10 code of Ankylosing Spondylitis and ICD9 code

ICD-10 and ICD-9 codes for Ankylosing Spondylitis, with classification details for clinicians, coders and patients.

ICD9 and ICD10 codes of Ankylosing Spondylitis

The ICD-10 code for Ankylosing Spondylitis is M45, while the older ICD-9 classification is 720.0. These codes are essential for medical documentation, insurance billing, and tracking the prevalence of Ankylosing Spondylitis within healthcare systems worldwide.



What is the clinical significance of the Ankylosing Spondylitis classification?


Ankylosing Spondylitis is a chronic, systemic inflammatory rheumatic disease that primarily affects the axial skeleton, specifically the sacroiliac joints and the spine. By utilizing the specific ICD-10 code M45, rheumatologists can accurately document the progression of the disease, which often begins with inflammatory back pain and stiffness. Because Ankylosing Spondylitis can also manifest as peripheral joint involvement, such as shoulder or hip pain, precise coding ensures that multisystem complications—including those involving the digestive, muscular, and immune systems—are properly linked to the primary diagnosis.



How does the diagnosis of Ankylosing Spondylitis impact patients?


Receiving a diagnosis of Ankylosing Spondylitis can be an overwhelming experience, often following years of unexplained back pain. Our community at DiseaseMaps.org, which currently includes 2,109 members living with Ankylosing Spondylitis, highlights that early and accurate coding is the first step toward accessing appropriate rheumatological care. While the condition can lead to significant skeletal changes, modern management strategies aim to reduce inflammation and maintain mobility, helping patients manage the physical and emotional burden of the disease.



What are the primary systems affected by Ankylosing Spondylitis?


Ankylosing Spondylitis is not merely a spinal condition; it is a systemic disease that requires a multidisciplinary approach. The following systems are frequently monitored by clinicians managing the condition:



  • Skeletal System: Inflammation of the sacroiliac joints and spinal vertebrae, which can lead to fusion.

  • Immune System: The underlying driver of the chronic inflammation associated with Ankylosing Spondylitis.

  • Muscular System: Enthesitis, or inflammation at the sites where tendons and ligaments attach to bone.

  • Digestive System: A subset of patients may experience associated inflammatory bowel conditions.

  • Nervous System: Potential complications arising from spinal nerve root compression or instability.



Is there a cure for Ankylosing Spondylitis?


Currently, there is no known cure for Ankylosing Spondylitis, but treatments have evolved significantly. While some patients explore herbal supplements to manage symptoms, these should never replace evidence-based medical treatments prescribed by a rheumatologist. Standard care for Ankylosing Spondylitis typically involves non-steroidal anti-inflammatory drugs (NSAIDs), physical therapy, and, in more severe cases, biologic disease-modifying antirheumatic drugs (DMARDs) to suppress the immune system's inflammatory response.



Next steps



  • Consult a Rheumatologist: Seek a formal evaluation if you have chronic inflammatory back pain that improves with exercise but not with rest.

  • Join the Community: Connect with the 2,109 members at DiseaseMaps.org to share experiences and coping strategies for managing life with Ankylosing Spondylitis.

  • Document Symptoms: Keep a detailed log of your joint stiffness, pain levels, and digestive health to assist your doctor in tracking your progress.

  • Physical Therapy: Work with a specialist to develop a customized exercise program to maintain spinal flexibility.



Medical disclaimer: This information is for educational purposes only and does not constitute professional medical advice, diagnosis, or treatment; always seek the advice of your physician or other qualified health provider with any questions regarding a medical condition.



References



  • NIH Genetic and Rare Diseases (GARD) Information Center: Ankylosing Spondylitis.

  • Orphanet: Rare disease database, ORPHA:823.

  • OMIM (Online Mendelian Inheritance in Man): Entry 106300 (Ankylosing Spondylitis).

  • Spondylitis Association of America (SAA): Patient resources and clinical guidelines.

Author: DiseaseMaps Editorial Team
Reviewed against authoritative medical sources (NIH GARD, Orphanet, OMIM)
Last updated: 2026-04-07
Medical disclaimer: This information does not substitute professional medical advice. Always consult your doctor before making health decisions.
Source: DiseaseMaps.org
10 answers
ICD10 code is M45
ICD9 code is 720

Posted May 19, 2017 by Kylie Frost 2120
both refer to diagnosing deseases

Posted Aug 31, 2017 by BigStu111 12832
The American version of M45.9 and other international versions. These Codes can be used to indicate a diagnosis for reimbursement purposes.

Posted Sep 6, 2017 by Daniel Wilson 2010
M45 - Ankylosing spondylitis
ICD-10M45.0 - Ankylosing spondylitis of multiple sites in spine
ICD-10M45.1 - Ankylosing spondylitis of occipito-atlanto-axial region
ICD-10M45.2 - Ankylosing spondylitis of cervical region
ICD-10M45.3 - Ankylosing spondylitis of cervicothoracic region
ICD-10M45.4 - Ankylosing spondylitis of thoracic region
ICD-10M45.5 - Ankylosing spondylitis of thoracolumbar region
ICD-10M45.6 - Ankylosing spondylitis lumbar region
ICD-10M45.7 - Ankylosing spondylitis of lumbosacral region
ICD-10M45.8 - Ankylosing spondylitis sacral and sacrococcygeal region
ICD-10M45.9 - Ankylosing spondylitis of unspecified sites in spine
ICD-9: 720.0
Short Description: Ankylosing spondylitis

Posted Sep 7, 2017 by Luciano Scariano 2600
ICD codes is the international classifications of diseases; a categorized list of diseases ABs their causes, symptoms, etc.

Posted Sep 10, 2017 by Sal 4050
The ICD-10 code sets are not a simple update of the ICD-9 code set. The ICD-10 code sets have
fundamental changes in structure and concepts that make them very different from ICD-9. Because of
these differences, it is important to develop a preliminary understanding of the changes from ICD-9 to
ICD-10. This basic understanding of the differences will then identify more detailed training that will be
needed to appropriately use the ICD-10 code sets. In addition, seeing the differences between the code
sets will raise awareness of the complexities of converting to the ICD-10 codes.

Posted Sep 21, 2017 by Rana Navid Anwaar Khan 3945
Icd9 classificazione internazionale malattie e dei problemi correlati
Icd10 decima revisione dello standard di classificazione di studi statistici ed epidemiologici

Posted Oct 1, 2017 by Silvia 2500
I didn't know about these codes.
I had to google it.
And it doesn't really resonate to me as this is unknown system to me.

Posted Feb 16, 2018 by Laeti 3570
ICD9 CODE 720.0. ICD10 CODE M45

Posted Jun 1, 2018 by Colleen 2550

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