I believe people with AS can work in sedentary jobs or jobs that don't require heavy lifting and alot of bending, stooping, walking, etx, and allow for breaks as we have to get up and down at times due to pain and stiffness. In early stages of is easier than when it progresses. As a nurse it took me almost 15 years to get diagnosed and I worked up until last 2 years and I'm not longer able to now. It was to physical with lifting and pushing heavy med carts and such. Due to back being so fragile and other joints as well that are affected it is very difficult to carry out even small task at times. So I would say as the disease progresses a large % are unable to work due to pain and fusion or illness from treatment or just put bodies staying sick and missing work so much and requiring special axxomadsrions most work places want allow. If I had to guess maybe 50% work