Modvigil 200 is generally well-tolerated, but it can increase heart rate and blood pressure, which may pose risks for individuals with pre-existing heart conditions. While serious heart problems are rare, Modvigil acts as a stimulant and may lead to palpitations, chest discomfort, or arrhythmias in some users, especially those with hypertension, heart disease, or a history of cardiovascular issues. If you have any heart-related concerns, it's important to consult a doctor before taking Modvigil to ensure it's safe for you. Regular monitoring of blood pressure and heart rate is recommended.