Short answer · Medically reviewed summary · Last updated: 2026-05-08
Chronic Granulomatous Disease (CGD) is classified under the ICD-10 code D71, which refers to "Functional disorders of polymorphonuclear neutrophils." In the older ICD-9 coding system, Chronic Granulomatous Disease was categorized under 288.1, representing "Functional disorders of neutrophils." What is Chronic Granulomatous Disease? Chronic Granulomatous Disease is a rare primary immunodeficiency disorder that affects the ability of phagocytes—a type of white blood cell—to kill certain bacteria and fungi. Because the immune system cannot effectively eliminate these pathogens, individuals with Chronic Granulomatous Disease are susceptible to recurrent, severe infections and the formation of inflammatory nodules called granulomas.
1 people with Chronic Granulomatous Disease have shared their first-person experience on this question at DiseaseMaps.
ICD10 code of Chronic Granulomatous Disease and ICD9 code
ICD-10 and ICD-9 codes for Chronic Granulomatous Disease, with classification details for clinicians, coders and patients.
Chronic Granulomatous Disease (CGD) is classified under the ICD-10 code D71, which refers to "Functional disorders of polymorphonuclear neutrophils." In the older ICD-9 coding system, Chronic Granulomatous Disease was categorized under 288.1, representing "Functional disorders of neutrophils."
What is Chronic Granulomatous Disease?
Chronic Granulomatous Disease is a rare primary immunodeficiency disorder that affects the ability of phagocytes—a type of white blood cell—to kill certain bacteria and fungi. Because the immune system cannot effectively eliminate these pathogens, individuals with Chronic Granulomatous Disease are susceptible to recurrent, severe infections and the formation of inflammatory nodules called granulomas. Our community at DiseaseMaps.org currently includes 60 members who navigate the daily realities of living with this condition.
How is Chronic Granulomatous Disease diagnosed?
Diagnosis of Chronic Granulomatous Disease typically involves specialized laboratory testing to assess the function of the NADPH oxidase enzyme complex. The most common diagnostic tools include:
- Dihydrorhodamine (DHR) flow cytometry: The gold standard test to measure the oxidative burst of neutrophils.
- Nitroblue tetrazolium (NBT) test: A traditional diagnostic method, though now largely replaced by flow cytometry.
- Genetic mutation analysis: Used to confirm the specific inheritance pattern and assist in family counseling.
Is Chronic Granulomatous Disease hereditary?
Yes, Chronic Granulomatous Disease is a genetic condition. It can be inherited in two ways: X-linked recessive (the most common form, accounting for approximately 65-70% of cases) or autosomal recessive. Because Chronic Granulomatous Disease is inherited, genetic counseling is highly recommended for families planning to have children to understand the risk of recurrence.
Next steps
- Consult with a clinical immunologist specializing in primary immunodeficiency disorders.
- Connect with the 60 members of the Chronic Granulomatous Disease community on DiseaseMaps.org to share experiences and coping strategies.
- Visit the Immune Deficiency Foundation (IDF) to access disease-specific patient resources and clinical trial information.
Medical disclaimer: This information is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment from a qualified healthcare provider.
References
- NIH Genetic and Rare Diseases Information Center (GARD): Chronic Granulomatous Disease.
- Orphanet: Rare disease database entry for Chronic Granulomatous Disease (ORPHA:378).
- OMIM (Online Mendelian Inheritance in Man): Clinical synopsis for Chronic Granulomatous Disease.
- Immune Deficiency Foundation (IDF): Educational resources for CGD patients and families.
Posted Dec 24, 2017 by carrie123 3550
