Short answer · Medically reviewed summary · Last updated: 2026-05-08

The ICD-10 code for Chronic myelogenous leukemia (CML) is C92.1, and the ICD-9 code is 205.1. These classification codes are essential for medical billing, clinical documentation, and tracking the global prevalence of Chronic myelogenous leukemia (CML) within healthcare systems. What is the clinical classification of Chronic myelogenous leukemia (CML)? Chronic myelogenous leukemia (CML) is a myeloproliferative neoplasm characterized by the unregulated growth of myeloid cells in the bone marrow.

1 people with Chronic myelogenous leukemia (CML) have shared their first-person experience on this question at DiseaseMaps.

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ICD10 code of Chronic myelogenous leukemia (CML) and ICD9 code

ICD-10 and ICD-9 codes for Chronic myelogenous leukemia (CML), with classification details for clinicians, coders and patients.

ICD9 and ICD10 codes of Chronic myelogenous leukemia (CML)

The ICD-10 code for Chronic myelogenous leukemia (CML) is C92.1, and the ICD-9 code is 205.1. These classification codes are essential for medical billing, clinical documentation, and tracking the global prevalence of Chronic myelogenous leukemia (CML) within healthcare systems.



What is the clinical classification of Chronic myelogenous leukemia (CML)?


Chronic myelogenous leukemia (CML) is a myeloproliferative neoplasm characterized by the unregulated growth of myeloid cells in the bone marrow. Clinically, Chronic myelogenous leukemia (CML) is defined by the presence of the Philadelphia chromosome, a genetic translocation between chromosomes 9 and 22. Understanding these diagnostic codes helps patients and providers navigate insurance coverage and clinical research, especially for the 287 members currently sharing their experiences on DiseaseMaps.org.



How are ICD codes used for Chronic myelogenous leukemia (CML)?


ICD (International Classification of Diseases) codes provide a standardized language for medical professionals worldwide. While C92.1 is the primary code for Chronic myelogenous leukemia (CML), clinicians may also use supplemental codes to denote the phase of the disease. The clinical progression of Chronic myelogenous leukemia (CML) typically follows three distinct phases:



  • Chronic phase: The initial stage where the disease is usually indolent and responsive to tyrosine kinase inhibitor (TKI) therapy.

  • Accelerated phase: A transitional period where blasts increase in the blood or bone marrow, signaling more aggressive disease behavior.

  • Blast crisis: The final, acute-leukemia phase where blast cells exceed 20% of the blood or marrow, requiring intensive intervention.



Is Chronic myelogenous leukemia (CML) considered a rare disease?


While Chronic myelogenous leukemia (CML) accounts for approximately 15% of all adult leukemias, it is classified as a rare condition with an estimated annual incidence of 1 to 2 cases per 100,000 adults. Because of this rarity, connecting with the community at DiseaseMaps.org can be a vital source of peer support for those navigating the complexities of a Chronic myelogenous leukemia (CML) diagnosis.



Next steps



  • Consult a hematologist-oncologist to confirm your specific disease phase and treatment plan.

  • Verify your medical records reflect the correct C92.1 ICD-10 code for billing and insurance purposes.

  • Connect with the 287 members at DiseaseMaps.org to share experiences and coping strategies.

  • Visit the National Cancer Institute (NCI) website for the latest updates on TKI clinical trials.



Medical disclaimer: This information is for educational purposes only and does not constitute professional medical advice, diagnosis, or treatment; always seek the advice of your physician regarding any medical condition.



References



  • NIH Genetic and Rare Diseases Information Center (GARD): Chronic Myelogenous Leukemia.

  • Orphanet: Chronic Myeloid Leukemia (ORPHA:520).

  • World Health Organization (WHO): International Classification of Diseases, 10th Revision (ICD-10).

  • American Cancer Society: Key Statistics for Chronic Myeloid Leukemia.

Author: DiseaseMaps Editorial Team
Reviewed against authoritative medical sources (NIH GARD, Orphanet, OMIM)
Last updated: 2026-05-08
Medical disclaimer: This information does not substitute professional medical advice. Always consult your doctor before making health decisions.
Source: DiseaseMaps.org
2 answers
http://www.icd10data.com/ICD10CM/Codes

Posted Sep 29, 2017 by Steve 2500

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i was diagnosed in 10/2012. Undetectable on sprycel 100mg in 11/2015. 

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