Short answer · Medically reviewed summary · Last updated: 2026-05-08
The primary medical billing code for Common Variable Immunodeficiency (CVID) under ICD-10 is D83.0 (Immunodeficiency with predominant antibody antibody defects), while the legacy ICD-9 code is 279.06. These codes are essential for healthcare providers to document the diagnosis of Common Variable Immunodeficiency accurately for insurance and clinical tracking purposes. What exactly is Common Variable Immunodeficiency? Common Variable Immunodeficiency is a primary immunodeficiency disorder characterized by low levels of serum immunoglobulins (antibodies) and an impaired ability to produce specific antibodies in response to infections or vaccinations.
ICD10 code of Common Variable Immunodeficiency and ICD9 code
ICD-10 and ICD-9 codes for Common Variable Immunodeficiency, with classification details for clinicians, coders and patients.
The primary medical billing code for Common Variable Immunodeficiency (CVID) under ICD-10 is D83.0 (Immunodeficiency with predominant antibody antibody defects), while the legacy ICD-9 code is 279.06. These codes are essential for healthcare providers to document the diagnosis of Common Variable Immunodeficiency accurately for insurance and clinical tracking purposes.
What exactly is Common Variable Immunodeficiency?
Common Variable Immunodeficiency is a primary immunodeficiency disorder characterized by low levels of serum immunoglobulins (antibodies) and an impaired ability to produce specific antibodies in response to infections or vaccinations. While 22 members of the DiseaseMaps.org community have shared their experiences with Common Variable Immunodeficiency, it is estimated to affect approximately 1 in 25,000 to 1 in 50,000 individuals globally. Patients with Common Variable Immunodeficiency often suffer from recurrent bacterial infections, particularly in the respiratory and gastrointestinal tracts.
How is Common Variable Immunodeficiency diagnosed?
Diagnosis of Common Variable Immunodeficiency involves a thorough clinical evaluation by an immunologist. Physicians typically look for a combination of low IgG levels alongside low IgA and/or IgM levels, paired with a poor vaccine response. Because Common Variable Immunodeficiency is a diagnosis of exclusion, clinicians must rule out other causes of hypogammaglobulinemia, such as malignancies or medication side effects.
What are the primary clinical features of Common Variable Immunodeficiency?
The presentation of Common Variable Immunodeficiency varies significantly between individuals. Key clinical hallmarks include:
- Recurrent sinopulmonary infections (pneumonia, bronchitis, sinusitis).
- Chronic gastrointestinal issues, including malabsorption and diarrhea.
- An increased prevalence of autoimmune disorders, such as immune thrombocytopenia (ITP) or rheumatoid arthritis.
- Splenomegaly and persistent lymphadenopathy.
- Increased risk of certain malignancies, particularly lymphoma.
Next steps
- Consult a board-certified clinical immunologist to manage ongoing immunoglobulin replacement therapy (IGRT).
- Maintain a detailed log of infections and symptoms to share during specialist appointments.
- Connect with the community at DiseaseMaps.org to share experiences with others living with Common Variable Immunodeficiency.
- Regularly screen for autoimmune comorbidities as recommended by your primary care provider.
Medical disclaimer: This information is for educational purposes only and does not constitute professional medical advice, diagnosis, or treatment; always seek the advice of your physician with any questions regarding a medical condition.
References
- NIH Genetic and Rare Diseases Information Center (GARD): Common Variable Immunodeficiency
- Orphanet: Common Variable Immunodeficiency (ORPHA:457)
- OMIM (Online Mendelian Inheritance in Man): #240500
- Immune Deficiency Foundation (IDF): Understanding CVID
