Short answer · Medically reviewed summary · Last updated: 2026-04-07
Cyclic vomiting syndrome (CVS) is officially classified under ICD-10 code G43.A0 (Cyclic vomiting, in migraine, not intractable) or G43.A1 (Cyclic vomiting, in migraine, intractable). Under the older ICD-9-CM classification system, Cyclic vomiting syndrome was coded as 536.2. What is the clinical definition of Cyclic vomiting syndrome? Cyclic vomiting syndrome is a complex disorder characterized by recurrent, stereotypical episodes of severe nausea and vomiting that are separated by symptom-free intervals.
8 people with Cyclic vomiting syndrome have shared their first-person experience on this question at DiseaseMaps.
ICD10 code of Cyclic vomiting syndrome and ICD9 code
ICD-10 and ICD-9 codes for Cyclic vomiting syndrome, with classification details for clinicians, coders and patients.
Cyclic vomiting syndrome (CVS) is officially classified under ICD-10 code G43.A0 (Cyclic vomiting, in migraine, not intractable) or G43.A1 (Cyclic vomiting, in migraine, intractable). Under the older ICD-9-CM classification system, Cyclic vomiting syndrome was coded as 536.2.
What is the clinical definition of Cyclic vomiting syndrome?
Cyclic vomiting syndrome is a complex disorder characterized by recurrent, stereotypical episodes of severe nausea and vomiting that are separated by symptom-free intervals. Because Cyclic vomiting syndrome affects both the digestive system and the nervous system, it is often categorized as a functional gastrointestinal disorder with strong links to migraine pathways. With 863 members in the DiseaseMaps.org community, we recognize that this condition is often debilitating, leading to complications like dehydration, extreme thirst, and severe lethargy that frequently require emergency medical intervention.
How is Cyclic vomiting syndrome diagnosed and coded?
Diagnosis of Cyclic vomiting syndrome is primarily clinical, meaning physicians must rule out structural gastrointestinal abnormalities through endoscopy or imaging before reaching a diagnosis. The transition from ICD-9 code 536.2 to the more specific ICD-10 codes (G43.A0 and G43.A1) reflects the growing medical consensus that CVS is closely related to migraine pathophysiology. Proper coding is essential for insurance authorization of treatments, as the condition requires long-term management strategies rather than just acute intervention.
What are the primary treatment approaches for Cyclic vomiting syndrome?
Management of Cyclic vomiting syndrome focuses on both abortive therapies to stop an active episode and prophylactic medications to prevent future occurrences. Because the condition involves the nervous system, treatment is often multidisciplinary, involving neurologists and gastroenterologists. Common pharmacological strategies include:
- Prophylactic agents: Amitriptyline is frequently prescribed as a first-line preventative, often supplemented by Coenzyme Q10 (CoQ-10) and L-Carnitine to support mitochondrial function.
- Abortive medications: Triptans, such as Imitrex, are utilized when an episode is identified early, alongside anti-nausea medications (anti-emetics).
- Supportive care: IV hydration is standard during episodes to manage dehydration and electrolyte imbalances.
- Psychological support: Addressing the anxiety and depression associated with the unpredictable nature of Cyclic vomiting syndrome is a crucial component of holistic care.
How does the nervous system influence Cyclic vomiting syndrome?
The connection between the nervous system and the gut is central to understanding Cyclic vomiting syndrome. Many patients experience autonomic symptoms such as cold sweats, hot flashes, and restless legs during an episode. These symptoms suggest that the brain-gut axis is dysregulated during a flare, potentially triggered by stress, certain foods, or hormonal changes. Recognizing these triggers is a key step for patients managing their health and reducing the frequency of hospitalizations.
Next steps
- Consult a gastroenterologist or neurologist who specializes in autonomic disorders to establish a personalized management plan.
- Maintain a detailed symptom diary to identify potential triggers for your Cyclic vomiting syndrome episodes.
- Connect with the 863 members of the DiseaseMaps.org community to share experiences and coping strategies.
- Discuss the suitability of mitochondrial supplements like L-Carnitine and CoQ-10 with your prescribing physician.
Medical disclaimer: This information is for educational purposes only and does not constitute professional medical advice, diagnosis, or treatment; always seek the advice of your physician or other qualified health provider with any questions regarding a medical condition.
References
- NIH Genetic and Rare Diseases Information Center (GARD): Cyclic Vomiting Syndrome.
- Orphanet (ORPHA:93952): Cyclic vomiting syndrome.
- OMIM (Online Mendelian Inheritance in Man): Cyclic vomiting syndrome susceptibility.
- CVSA (Cyclic Vomiting Syndrome Association): Clinical guidelines and patient resources.
other codes applicable would be;
*G00-G99-disease of the nervous system, and
*G43-migraine
The ICD9 code for Cyclic Vomiting Syndrome is 536.3-persistant vomiting
Posted Jan 27, 2018 by Laura 3890
ICD-10-CM Codes › G00-G99 Diseases of the nervous system › G40-G47 Episodic and paroxysmal disorders › G43- Migraine › 2018 ICD-10-CM Diagnosis Code G43.A0
Cyclical vomiting, not intractable
2016 2017 2018 Billable/Specific Code
G43.A0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
The 2018 edition of ICD-10-CM G43.A0 became effective on October 1, 2017.
This is the American ICD-10-CM version of G43.A0 - other international versions of ICD-10 G43.A0 may differ.
Applicable To
Cyclical vomiting, without refractory migraine
The following code(s) above G43.A0 contain annotation back-references that may be applicable to G43.A0:
G00-G99 Diseases of the nervous system
G43 Migraine
Approximate Synonyms
Cyclical vomiting
Cyclical vomiting syndrome
Cyclical vomiting with status migrainosus
Vomiting, cyclic
ICD-10-CM G43.A0 is grouped within Diagnostic Related Group(s) (MS-DRG v35.0):
102 Headaches with mcc
103 Headaches without mcc
Convert G43.A0 to ICD-9-CM
Code History
2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
Diagnosis Index entries containing back-references to G43.A0:
Cyclical vomiting G43.A0 - see also Vomiting, cyclical
Vomiting R11.10
cyclical G43.A0
not intractable G43.A0
without refractory migraine G43.A0
Posted Feb 19, 2018 by Rachel 4410
Posted May 29, 2019 by Nicci 3070
2019 ICD-10-CM Diagnosis Code G43.A0: Cyclical vomiting, not intractable.
Posted May 30, 2019 by Chloe 3120
G43.A0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
The 2019 edition of ICD-10-CM G43.A0 became effective on October 1, 2018.
This is the American ICD-10-CM version of G43.A0 - other international versions of ICD-10 G43.A0 may differ.
Posted May 30, 2019 by Cassandra Katharina Minerva 4050
other codes applicable would be;
*G00-G99-disease of the nervous system, and
*G43-migraine
The ICD9 code for Cyclic Vomiting Syndrome is 536.3 -persistent vomiting
Posted Jul 12, 2021 by CVS Network - Angie 2875
ICD-10: vomito ciclicos
Posted Nov 3, 2017 by Betty 1700
CYCLIC 536.2
associated with migraine 346.2
Psicogena 306.4
Posted Nov 4, 2017 by Fanny 2000
