Short answer · Medically reviewed summary · Last updated: 2026-05-08
While there is no scientifically proven "natural cure" for Dermatillomania (also known as Excoriation Disorder), several complementary approaches may help manage the underlying anxiety and stress that often trigger skin-picking episodes. It is essential to view these as supportive measures alongside, rather than replacements for, evidence-based treatments like Cognitive Behavioral Therapy (CBT). What supplements are studied for Dermatillomania? The most widely researched supplement for Dermatillomania is N-acetylcysteine (NAC).
3 people with Dermatillomania have shared their first-person experience on this question at DiseaseMaps.
While there is no scientifically proven "natural cure" for Dermatillomania (also known as Excoriation Disorder), several complementary approaches may help manage the underlying anxiety and stress that often trigger skin-picking episodes. It is essential to view these as supportive measures alongside, rather than replacements for, evidence-based treatments like Cognitive Behavioral Therapy (CBT).
The most widely researched supplement for Dermatillomania is N-acetylcysteine (NAC). A clinical study published in the American Journal of Psychiatry indicated that NAC, an amino acid derivative, may help reduce the urge to pick by modulating glutamate levels in the brain. Other supplements, such as Inositol or St. John’s Wort, are frequently discussed in patient communities, but evidence for their efficacy in treating Dermatillomania is largely anecdotal and lacks robust clinical trial support.
Mind-body practices aim to increase awareness of the physical sensations preceding a picking episode. Many individuals with Dermatillomania find the following techniques helpful for grounding and emotional regulation:
Natural does not always mean safe. Supplements can interact negatively with SSRIs or other psychiatric medications commonly prescribed for Dermatillomania. For example, St. John’s Wort can interfere with the metabolism of many conventional drugs, potentially leading to dangerous side effects or reduced efficacy. Always consult your psychiatrist or primary care physician before adding any new supplement to your regimen to ensure it does not counteract your existing treatment plan for Dermatillomania.
Medical disclaimer: This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment.