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Hi In my experience while living with Addison's Disease , my worse symptoms would have to be the SEVERE FATIGUE daily. This has impacted my life tremendously. . Just trying to get myself washed and dressed takes all the good from me. It exacerbates the fatigue. Next would have to be the PERFUSE PERSPIRING , then would come PAIN, .These symptoms in which I mention are daily and if I could rid any of the complete symptoms I would have to say the above. In saying that there are so many more which impacts my daily living. Feeling like I'm in a fog or even feeling stupid if you would.. Drunk like feeling. There are many more but the first three would be my wish to have gone from my life.