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Yes, but you can be a carrier of the genetic components without having the condition/symptoms. I have several DNA polymorphism contributors in the SP7, TNXB, ADAMST2, PLOD1, COL1A2, COL27A1, COL3A1, COL5A1, COL5A2, COL6A3 and LEPRE1 genes. So in layman terms I have Classic and Hypermobility EDS with crossovers of Vascular, Arthrochalasia and Kyphoscoliosis types, as well as Osteogenesis Imperfecta and Bethlem Myopathy.