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Symptoms are varied; too many to list here. Lyme is the 'great imitator' and can resemble many illnesses/conditions. Among the most helpful tip is to look at Fibromyalgia and MS symptoms as they are often similar. Most Lyme is clinically diagnosed by a qualified practitioner (MD, ND), not through blood tests and certainly not by an infectious disease 'specialist' (with the possible exception of acute infection in its earliest stages).