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Congenital Panhypopituitarism with the following issues as well: Hypothyroidism, Septo optic in left eye (blind in left eye), adrenal insufficiency, growth hormone deficiency, and Autoimmune deficiency. The worst symptoms are the leg pain that is experienced, as well as the risk of getting sick. You always have to worry about getting a sick...with anything... since the common cold can kill you.