Short answer · Medically reviewed summary · Last updated: 2026-05-08
Factor VII deficiency is classified under the ICD-10-CM code D68.32 (Hemorrhagic disorder due to factor VII deficiency). In the older ICD-9-CM system, this condition was coded as 286.3 (Congenital deficiency of other clotting factors). What is the clinical significance of Factor VII deficiency? Factor VII deficiency is a rare inherited bleeding disorder caused by a lack of or dysfunction in the coagulation protein Factor VII.
ICD10 code of Factor VII Deficiency and ICD9 code
ICD-10 and ICD-9 codes for Factor VII Deficiency, with classification details for clinicians, coders and patients.
Factor VII deficiency is classified under the ICD-10-CM code D68.32 (Hemorrhagic disorder due to factor VII deficiency). In the older ICD-9-CM system, this condition was coded as 286.3 (Congenital deficiency of other clotting factors).
What is the clinical significance of Factor VII deficiency?
Factor VII deficiency is a rare inherited bleeding disorder caused by a lack of or dysfunction in the coagulation protein Factor VII. Because this protein is essential for the initiation of the blood-clotting cascade, individuals with Factor VII deficiency may experience symptoms ranging from mild bruising and mucosal bleeding to severe, life-threatening intracranial hemorrhages. At DiseaseMaps.org, we currently support a community of 40 people with Factor VII deficiency who share their experiences managing this condition.
How is the severity of Factor VII deficiency assessed?
Clinical presentation does not always correlate perfectly with laboratory levels of Factor VII activity. However, clinicians typically categorize the severity of Factor VII deficiency based on the following plasma activity levels:
- Mild: Factor VII levels between 20% and 50% of normal.
- Moderate: Factor VII levels between 5% and 20% of normal.
- Severe: Factor VII levels below 1-2% of normal.
Is Factor VII deficiency hereditary?
Yes, Factor VII deficiency is an autosomal recessive disorder, meaning an individual must inherit a mutated F7 gene from both parents to manifest the disease. Because it is rare—occurring in approximately 1 in 300,000 to 500,000 people globally—genetic counseling is highly recommended for families affected by Factor VII deficiency to understand recurrence risks.
Next steps
- Consult a hematologist specializing in coagulation disorders to establish a personalized bleeding management plan.
- Join the community of 40 patients at DiseaseMaps.org to connect with others living with Factor VII deficiency.
- Request a referral to a certified genetic counselor to discuss family planning and inheritance patterns.
- Carry a medical alert identification card specifying your diagnosis of Factor VII deficiency at all times.
Medical disclaimer: This information is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment from a qualified healthcare provider.
References
- Orphanet: Factor VII deficiency (ORPHA:327)
- NIH GARD: Factor VII deficiency (GARD ID: 6368)
- OMIM: Coagulation Factor VII Deficiency (Entry #227500)
- World Federation of Hemophilia (WFH): Guidelines for the Management of Rare Bleeding Disorders
