Short answer · Medically reviewed summary · Last updated: 2026-05-08
Factor XIII deficiency is a rare congenital bleeding disorder also known as fibrin stabilizing factor deficiency or Laki-Lorand factor deficiency. While medical professionals most commonly use the term Factor XIII deficiency, patients may encounter various historical and clinical synonyms in older medical literature or international records. What are the common synonyms for Factor XIII deficiency? Because Factor XIII deficiency was identified through various research pathways, it has been referred to by several names over the decades.
Factor XIII Deficiency synonyms
Other names for Factor XIII Deficiency: synonyms, acronyms and related terms used by doctors and patients.
Factor XIII deficiency is a rare congenital bleeding disorder also known as fibrin stabilizing factor deficiency or Laki-Lorand factor deficiency. While medical professionals most commonly use the term Factor XIII deficiency, patients may encounter various historical and clinical synonyms in older medical literature or international records.
What are the common synonyms for Factor XIII deficiency?
Because Factor XIII deficiency was identified through various research pathways, it has been referred to by several names over the decades. Clinicians and researchers primarily use the term Factor XIII deficiency today to ensure clarity. However, you may see the following names in medical charts or older publications:
- Fibrin stabilizing factor deficiency
- Laki-Lorand factor deficiency
- Fibrinase deficiency
- Congenital Factor XIII deficiency
- Fibrin-stabilizing factor (FSF) deficiency
Why does this condition have multiple names?
The naming of Factor XIII deficiency is rooted in the history of hematology. In the mid-20th century, researchers like Kálmán Laki and László Loránd identified the protein responsible for cross-linking fibrin, leading to the name "Laki-Lorand factor." As international medical standards moved toward a numerical system for clotting factors (the Roman numeral system), the term Factor XIII deficiency became the official nomenclature to standardize reporting across global health systems.
How is this disease classified in medical systems?
Standardized databases provide specific identifiers to help patients and doctors navigate records. In the Online Mendelian Inheritance in Man (OMIM) database, it is cataloged under #613225 and #613235. Orphanet recognizes the condition under ORPHA:324. These classification systems help differentiate Factor XIII deficiency from other rare coagulation disorders, ensuring that research and clinical trials are accurately categorized.
Next steps
- Consult with a hematologist who specializes in rare coagulation disorders to discuss your specific variant.
- Connect with the 5 community members on DiseaseMaps.org who are currently living with Factor XIII deficiency to share experiences.
- Request a genetic consultation to understand the inheritance pattern of your specific diagnosis.
Medical disclaimer: This content is for informational purposes only and does not constitute professional medical advice, diagnosis, or treatment; always seek the advice of your physician regarding a medical condition.
References
- Orphanet: Factor XIII deficiency (ORPHA:324)
- NIH Genetic and Rare Diseases Information Center (GARD): Factor XIII deficiency
- OMIM: Fibrin stabilizing factor, A subunit; F13A1 (#613225)
- World Federation of Hemophilia (WFH) Guidelines on Rare Bleeding Disorders
