Short answer · Medically reviewed summary · Last updated: 2026-04-07

Gestational trophoblastic disease (GTD) is primarily coded under ICD-10 code O01 (Hydatidiform mole), while specific malignant forms fall under categories O01.0 through O01.9. In the older ICD-9 classification system, this condition was generally categorized under code 630 (Hydatidiform mole). What exactly is Gestational trophoblastic disease? Gestational trophoblastic disease refers to a group of rare, pregnancy-related tumors that develop from cells that normally form the placenta.

2 people with Gestational trophoblastic disease have shared their first-person experience on this question at DiseaseMaps.

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ICD10 code of Gestational trophoblastic disease and ICD9 code

ICD-10 and ICD-9 codes for Gestational trophoblastic disease, with classification details for clinicians, coders and patients.

ICD9 and ICD10 codes of Gestational trophoblastic disease

Gestational trophoblastic disease (GTD) is primarily coded under ICD-10 code O01 (Hydatidiform mole), while specific malignant forms fall under categories O01.0 through O01.9. In the older ICD-9 classification system, this condition was generally categorized under code 630 (Hydatidiform mole).



What exactly is Gestational trophoblastic disease?


Gestational trophoblastic disease refers to a group of rare, pregnancy-related tumors that develop from cells that normally form the placenta. These cells, known as trophoblasts, grow abnormally after fertilization. While Gestational trophoblastic disease is often benign, such as in the case of a complete or partial hydatidiform mole, some forms can be malignant, including choriocarcinoma, placental site trophoblastic tumors, or epithelioid trophoblastic tumors. Understanding the classification is vital for both clinical management and accurate medical billing via ICD coding.



How are the ICD-10 and ICD-9 codes used for Gestational trophoblastic disease?


Medical coding is essential for healthcare providers to track the incidence and treatment of Gestational trophoblastic disease. While ICD-9 (630) is largely historical, the ICD-10 system provides a more granular approach to documenting the condition:



  • O01.0: Classical hydatidiform mole

  • O01.1: Incomplete and partial hydatidiform mole

  • O01.9: Hydatidiform mole, unspecified

  • O02.0: Blighted ovum and non-hydatidiform mole


Clinicians utilize these codes to ensure that patients receive specialized care pathways, as Gestational trophoblastic disease often requires monitoring of human chorionic gonadotropin (hCG) levels to rule out persistent disease or malignancy.



What is the clinical significance of these classifications?


For the 406 members of the DiseaseMaps.org community living with or recovering from Gestational trophoblastic disease, these codes represent more than just administrative data. Accurate coding ensures that insurance providers recognize the necessity of long-term follow-up and specialized oncological or gynecological care. Because Gestational trophoblastic disease can rarely progress to malignancy, precise documentation is a cornerstone of patient safety, ensuring that physicians can track progression or regression effectively.



How does the diagnosis process work?


The diagnosis of Gestational trophoblastic disease typically involves a combination of pelvic ultrasound, serum hCG testing, and histopathological examination of tissue following a pregnancy event. Because the condition is rare, early detection is critical. The clinical team focuses on identifying the specific subtype, as the treatment protocol for a benign mole differs significantly from the chemotherapy often required for malignant trophoblastic tumors.



Next steps



  • Consult a gynecologic oncologist who specializes in Gestational trophoblastic disease for personalized care.

  • Keep a detailed record of your hCG levels and pathology reports to share with your healthcare team.

  • Connect with the 406 other members on DiseaseMaps.org to share experiences and find emotional support within the community.

  • Ask your provider about long-term surveillance protocols to ensure your health remains stable post-treatment.



Medical disclaimer: This information is for educational purposes only and does not constitute professional medical advice, diagnosis, or treatment; always seek the advice of your physician with any questions regarding a medical condition.



References



  • Orphanet: Rare disease database entry for Gestational Trophoblastic Tumors (ORPHA:885).

  • NIH GARD: Genetic and Rare Diseases Information Center guidelines on Hydatidiform Mole and GTD.

  • World Health Organization (WHO): International Classification of Diseases (ICD-10) documentation for pregnancy-related complications.

  • American Cancer Society: Clinical resources regarding the diagnosis and staging of gestational trophoblastic disease.

Medical disclaimer: This information does not substitute professional medical advice. Always consult your doctor before making health decisions.
Source: DiseaseMaps.org
3 answers
The ICD10 code is 001.9
The ICD9 code is 181

Posted Sep 26, 2017 by Cindy 2120
ICD-9-CM Diagnosis Code 181
ICD-10-CM Diagnosis Code O01.9

Posted Nov 6, 2017 by MCHill 3050

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Stories of Gestational trophoblastic disease

GESTATIONAL TROPHOBLASTIC DISEASE STORIES
Gestational trophoblastic disease stories
https://www.facebook.com/sarah.arends.0927/posts/10153842187923073
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October 2014 I was "pregnant" . My hcg was not co corresponding to my weeks of pregnancy and I started to bleed . I was referred to have a scan but nothing could be made out so it was decided to be done again in 2 weeks. 2 weeks passed and the scan w...
Gestational trophoblastic disease stories
Had a tumor in my uterus that was a pound and a half in size. Diagnosed 03-04-13, hysterectomy 03-05-13. HCG's were well above 400K when they stopped counting. Monitored hcg levels for one year. Last check they were 2. 
Gestational trophoblastic disease stories
My baby was born full term and I wasn't diagnosed until she was 4 months old and after 12 hours of tests and misdiagnosis of a miscarriage,  a heavy menstrual cycle or another pregnancy. After I had a massive hemorrhage, one dr ordered a stat bhcg l...
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Hello, my name is Kayla. I am 23 engaged and have a beautiful little girl. I had Ebony January 14 2013. In June of 2014 I had my first molar pregnancy. I was not pregnant. They removed the molar. I have been on birth control since my daughter was bor...

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