Short answer · Medically reviewed summary · Last updated: 2026-04-07
Goodpasture syndrome is classified under the ICD-10 code M31.0 (Goodpasture’s syndrome) and the ICD-9 code 446.21 (Goodpasture’s syndrome). These standardized codes are essential for medical billing, clinical documentation, and tracking the prevalence of this rare autoimmune disorder within global health systems. What is the clinical nature of Goodpasture syndrome? Goodpasture syndrome, also known as anti-glomerular basement membrane (anti-GBM) disease, is a rare autoimmune condition where the body’s immune system produces antibodies that attack the basement membranes in the kidneys and the lungs.
2 people with Goodpasture syndrome have shared their first-person experience on this question at DiseaseMaps.
ICD10 code of Goodpasture syndrome and ICD9 code
ICD-10 and ICD-9 codes for Goodpasture syndrome, with classification details for clinicians, coders and patients.
Goodpasture syndrome is classified under the ICD-10 code M31.0 (Goodpasture’s syndrome) and the ICD-9 code 446.21 (Goodpasture’s syndrome). These standardized codes are essential for medical billing, clinical documentation, and tracking the prevalence of this rare autoimmune disorder within global health systems.
What is the clinical nature of Goodpasture syndrome?
Goodpasture syndrome, also known as anti-glomerular basement membrane (anti-GBM) disease, is a rare autoimmune condition where the body’s immune system produces antibodies that attack the basement membranes in the kidneys and the lungs. Because Goodpasture syndrome can lead to rapidly progressive glomerulonephritis and pulmonary hemorrhage, prompt medical identification using the correct ICD codes is critical for securing insurance coverage for urgent treatments like plasmapheresis and immunosuppressive therapy. At DiseaseMaps.org, 108 people with Goodpasture syndrome have joined our community, helping to map the diagnostic journeys and treatment outcomes of others facing this challenging condition.
How are ICD codes used for Goodpasture syndrome?
Medical coding provides a universal language for healthcare providers to describe Goodpasture syndrome. While ICD-10-CM (Clinical Modification) code M31.0 is the current standard in the United States and many other countries, the older ICD-9 code 446.21 is still occasionally encountered in historical medical records. Accurate coding is vital for several reasons:
- Insurance Authorization: Ensures that high-cost treatments, such as cyclophosphamide or rituximab, are covered by providers.
- Clinical Research: Allows researchers to aggregate data to better understand the epidemiology of Goodpasture syndrome.
- Patient Advocacy: Helps rare disease organizations demonstrate the collective burden of the disease to policymakers and funding bodies.
What are the diagnostic markers for Goodpasture syndrome?
The diagnosis of Goodpasture syndrome is typically confirmed through a combination of clinical findings, serological tests, and tissue biopsy. Clinicians look for the presence of circulating anti-GBM antibodies in the blood via ELISA testing. In Goodpasture syndrome, a kidney biopsy often reveals a "linear" pattern of IgG deposition along the glomerular basement membrane when viewed under immunofluorescence microscopy. Because this is a medical emergency, rapid coordination between nephrologists and pulmonologists is necessary to mitigate long-term organ damage.
How do patients manage the emotional impact of Goodpasture syndrome?
Living with a rare, life-threatening illness like Goodpasture syndrome is physically and emotionally taxing. The uncertainty of kidney function and the intensity of immunosuppressive treatments can lead to significant psychological distress, including anxiety and depression. Connecting with others who share the diagnosis can provide a sense of validation. Our community of 108 members at DiseaseMaps.org offers a space where those affected by Goodpasture syndrome can share experiences, coping strategies, and support, which is an invaluable component of the healing process alongside medical intervention.
Next steps
- Consult a board-certified nephrologist or rheumatologist to discuss your specific medical records and treatment plan.
- Ensure your medical team is using the correct ICD-10 code (M31.0) to facilitate seamless communication between specialists and insurance providers.
- Join the Goodpasture syndrome community at DiseaseMaps.org to connect with others and track your health journey.
- Consider participating in clinical trials or registry studies to contribute to the global understanding of this rare condition.
Medical disclaimer: This content is for informational purposes only and does not constitute professional medical advice, diagnosis, or treatment; always seek the advice of your physician or other qualified health provider with any questions regarding a medical condition.
References
- National Institutes of Health (NIH) Genetic and Rare Diseases Information Center (GARD): Anti-glomerular basement membrane disease.
- Orphanet: Goodpasture syndrome (ORPHA:378).
- Online Mendelian Inheritance in Man (OMIM): Goodpasture syndrome entry.
- World Health Organization (WHO): International Classification of Diseases, 10th Revision (ICD-10).
ICD9 - 446.21
Posted Jul 6, 2017 by Paul 2200
ICD9 is -CM codes are used in medical billing and coding to describe diseases, injuries, symptoms and conditions. ICD-9-CM 446.21 is one of thousands of ICD-9-CM codes used in healthcare. Although ICD-9-CM and CPT codes are largely numeric, they differ in that CPT codes describe medical procedures and services. Can't find a code? Start at the root of ICD-9-CM, check the 2012 ICD-9-CM Index or use the search engine at the top of this page to lookup any code.
Posted Oct 9, 2017 by Debbie 2000
