The term “hemicrania continua” was coined by Sjaastad and Spierings (Sjaastad and Spierings 1984). They reported a woman aged 63 years and a man aged 53 years who developed a strictly unilateral headache that was continuous from onset and absolutely responsive to indomethacin. In 2006, Sjaastad reported the long-term follow-up of the first woman with hemicrania continua until her death at age 81. She was treated with indomethacin during the whole observation time; no tachyphylaxis was observed, but she developed gastric ulcers secondary to the indomethacin (Sjaastad 2006). In 1987, the first case of hemicrania continua with a remitting course was reported (Sjaastad and Tjorstad 1987).