HSP is a genetic disease. It is defined as "uncomplicated" if it affects only the lower extremities. It is either childhood or adult onset. Childhood onset has been shown to not be nearly as progressive and not progress as far as for those who are adult onset. Complicated HSP can affect other parts of the body and they can have additional symptoms, including impaired vision, ataxia, epilepsy, cognitive impairment, peripheral neuropathy, and/or deafness, occur. the different forms of hsp are caused by mutations in different genes. inheritance varies. there are no specific treatments to prevent, slow, or reverse hsp. individual symptoms may be treated with medications and/or physical therapy.