Short answer · Medically reviewed summary · Last updated: 2026-05-08
The ICD-10 code for Hypereosinophilic Syndrome is D72.1 (Elevated eosinophil count), while the ICD-9 code is 288.3 (Eosinophilia). These diagnostic codes are essential for healthcare providers to document Hypereosinophilic Syndrome accurately in medical records for billing and clinical tracking purposes. What is Hypereosinophilic Syndrome? Hypereosinophilic Syndrome is a rare, complex disorder characterized by the persistent overproduction of eosinophils, a type of white blood cell, leading to organ damage.
ICD10 code of Hypereosinophilic Syndrome and ICD9 code
ICD-10 and ICD-9 codes for Hypereosinophilic Syndrome, with classification details for clinicians, coders and patients.
The ICD-10 code for Hypereosinophilic Syndrome is D72.1 (Elevated eosinophil count), while the ICD-9 code is 288.3 (Eosinophilia). These diagnostic codes are essential for healthcare providers to document Hypereosinophilic Syndrome accurately in medical records for billing and clinical tracking purposes.
What is Hypereosinophilic Syndrome?
Hypereosinophilic Syndrome is a rare, complex disorder characterized by the persistent overproduction of eosinophils, a type of white blood cell, leading to organ damage. Because Hypereosinophilic Syndrome can affect the heart, lungs, skin, and nervous system, it requires a multidisciplinary medical approach to manage systemic inflammation and prevent long-term complications.
How is Hypereosinophilic Syndrome diagnosed?
Diagnosis of Hypereosinophilic Syndrome typically requires meeting three specific criteria: an absolute eosinophil count (AEC) greater than 1,500 cells/μL for at least six months, evidence of organ involvement, and the exclusion of secondary causes such as parasitic infections or allergies. Clinicians often use the following diagnostic tools for Hypereosinophilic Syndrome:
- Complete blood count (CBC) with differential to confirm persistent eosinophilia.
- Bone marrow biopsy to evaluate for clonal or neoplastic processes.
- Genetic testing, specifically looking for the FIP1L1-PDGFRA fusion gene, which is found in a subset of patients with Hypereosinophilic Syndrome.
- Echocardiograms and pulmonary function tests to assess organ-specific damage.
Is there a community for those living with Hypereosinophilic Syndrome?
Living with a rare condition can feel isolating, but you are not alone. Currently, 3 people with Hypereosinophilic Syndrome have joined the DiseaseMaps.org community to share their personal experiences, provide peer support, and discuss the daily realities of managing this diagnosis.
Next steps
- Consult with a hematologist or an immunologist who specializes in eosinophilic disorders.
- Request a referral for specialized genetic testing to determine if your Hypereosinophilic Syndrome is linked to specific gene mutations.
- Join the DiseaseMaps.org community to connect with others currently navigating Hypereosinophilic Syndrome.
- Keep a detailed symptom journal to assist your care team in tracking treatment efficacy.
Medical disclaimer: This information is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment.
References
- NIH Genetic and Rare Diseases Information Center (GARD): Hypereosinophilic Syndrome.
- Orphanet: Hypereosinophilic syndrome (ORPHA:2513).
- OMIM (Online Mendelian Inheritance in Man): Entry #607685.
- American Partnership for Eosinophilic Disorders (APFED).
