Short answer · Medically reviewed summary · Last updated: 2026-05-08

Exercise is generally recommended for individuals with Multiple myeloma, as it helps mitigate cancer-related fatigue, maintains bone density, and improves overall physical function. Before beginning any routine, it is essential to obtain medical clearance from your hematologist or oncologist to ensure your specific bone health and blood count levels are safe for activity. Is exercise safe for patients with Multiple myeloma? Yes, physical activity is a vital component of supportive care for Multiple myeloma.

3 people with Multiple myeloma have shared their first-person experience on this question at DiseaseMaps.

6

Is it advisable to do exercise when affected by Multiple myeloma? Which activities would you suggest and how intense should they be?

Exercise with Multiple myeloma: which activities patients recommend or avoid, and what the evidence says.

Multiple myeloma sports

Exercise is generally recommended for individuals with Multiple myeloma, as it helps mitigate cancer-related fatigue, maintains bone density, and improves overall physical function. Before beginning any routine, it is essential to obtain medical clearance from your hematologist or oncologist to ensure your specific bone health and blood count levels are safe for activity.



Is exercise safe for patients with Multiple myeloma?


Yes, physical activity is a vital component of supportive care for Multiple myeloma. While the disease can cause bone lesions and increased fracture risk, a tailored exercise program can help maintain muscle mass and bone strength. The goal is to move safely, focusing on low-impact activities that minimize stress on the skeletal system while boosting cardiovascular health and mood.



What types of exercise are recommended for Multiple myeloma?


When living with Multiple myeloma, consistency is more important than intensity. Focus on activities that improve balance and functional strength:



  • Walking: A low-impact way to improve cardiovascular endurance.

  • Water-based exercise: Swimming or aquatic therapy provides resistance without gravity-based impact on weakened bones.

  • Gentle Yoga or Tai Chi: Excellent for flexibility, balance, and stress reduction.

  • Light Resistance Training: Using resistance bands or light weights to maintain muscle mass, provided they are cleared by your care team.



Which activities should be avoided with Multiple myeloma?


Due to the risk of pathological fractures associated with Multiple myeloma, you should avoid high-impact activities such as running, jumping, or contact sports. Furthermore, avoid heavy lifting or exercises that involve significant spinal flexion or twisting, as these motions can place excessive pressure on vertebrae potentially weakened by the disease.



How can I safely manage my energy levels?


On days when you feel fatigued, utilize a "pacing" strategy. Instead of one long workout, try three 10-minute sessions throughout the day. Listen to your body; if you experience new or sharp pain, stop immediately and consult your medical team. With 217 community members on DiseaseMaps.org sharing their experiences, many find that working with a physical therapist specializing in oncology provides a safer, more structured path to fitness.



Next steps



  • Request a referral to an oncology-certified physical therapist.

  • Obtain a bone density scan (DEXA) to understand your specific fracture risk.

  • Join our DiseaseMaps.org community to connect with others managing Multiple myeloma.

  • Start with just 5–10 minutes of movement and gradually increase as your energy allows.



Medical disclaimer: This information is for educational purposes and should not replace professional medical advice; always consult your oncology team before starting an exercise program.



References



  • NIH National Cancer Institute (NCI) - Multiple Myeloma Treatment Overview

  • Multiple Myeloma Research Foundation (MMRF) - Living with Myeloma: Exercise Guidelines

  • American Cancer Society - Physical Activity and the Cancer Patient

  • Orphanet - Multiple Myeloma Clinical Care Standards

Author: DiseaseMaps Editorial Team
Reviewed against authoritative medical sources (NIH GARD, Orphanet, OMIM)
Last updated: 2026-05-08
Sources cited: NIH National Cancer Institute (NCI) - Multiple Myeloma Treatment Overview · Multiple Myeloma Research Foundation (MMRF) - Living with Myeloma: Exercise Guidelines · American Cancer Society - Physical Activity and the Cancer Patient · Orphanet - Multiple Myeloma Clinical Care Standards
Medical disclaimer: This information does not substitute professional medical advice. Always consult your doctor before making health decisions.
Source: DiseaseMaps.org
4 answers
Exercise is very important since exercise does much to maintain strength and flexibility. I suggest plenty of walking, yoga, and light to medium weight training.

Posted Jul 19, 2017 by Larry 2100
Anyone diagnosed with multiple myeloma should exercise as much as they're able to. The intensity should be what they are capable of doing. They can participate in any type of exercise.

Posted Jul 19, 2017 by Deb 2000
Always ask your doctor. I was told by my doctor that you could walk briskly every day and also riding a bike helps the hip area. I was advised I am not allowed to lift any weights.

Posted Jul 20, 2017 by Tammy Gallet Ward 2000

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