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What is the history of Oculopharyngeal muscular dystrophy?

When was Oculopharyngeal muscular dystrophy discovered? What is the story of this discovery? Was it coincidence or not?

History of Oculopharyngeal muscular dystrophy
2 answers
Yes. It was discovered in 1915 in a French Canadian family.

Posted May 18, 2017 by Monica 2150
Oculopharyngeal muscular dystrophy (OPMD) is a late-onset, dominantly inherited disorder characterized by progressive ptosis, dysphagia and proximal limb weakness. It was first described in 1915 (Taylor, 1915), when it was attributed to a progressive cranial neuropathy. However, in 1962, Victor and colleagues clearly demonstrated that the primary pathology was myopathic and that it was inherited in an autosomal dominant manner (Victor et al., 1962). Muscle histology in affected individuals typically reveals abnormal variability in fibre size, an increase in endomysial fibrosis, and cytoplasmic basophilic rimmed vacuoles similar to those seen in inclusion body myositis (Coquet et al., 1990). Ultrastructural studies on muscle in OPMD have demonstrated filamentous nuclear inclusions in a minority of fibres that are not seen in other inherited or acquired muscle diseases (Tomé and Fardeau, 1980).

https://academic.oup.com/brain/article/124/3/522/334351#89180107

Posted Feb 22, 2021 by James 2500

History of Oculopharyngeal muscular dystrophy

Oculopharyngeal muscular dystrophy life expectancy

What is the life expectancy of someone with Oculopharyngeal muscular dystro...

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Celebrities with Oculopharyngeal muscular dystrophy

Celebrities with Oculopharyngeal muscular dystrophy

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Is Oculopharyngeal muscular dystrophy hereditary?

Is Oculopharyngeal muscular dystrophy hereditary?

6 answers
Is Oculopharyngeal muscular dystrophy contagious?

Is Oculopharyngeal muscular dystrophy contagious?

4 answers
ICD9 and ICD10 codes of Oculopharyngeal muscular dystrophy

ICD10 code of Oculopharyngeal muscular dystrophy and ICD9 code

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Natural treatment of Oculopharyngeal muscular dystrophy

Is there any natural treatment for Oculopharyngeal muscular dystrophy?

4 answers
Living with Oculopharyngeal muscular dystrophy

Living with Oculopharyngeal muscular dystrophy. How to live with Oculophary...

5 answers
Oculopharyngeal muscular dystrophy diet

Oculopharyngeal muscular dystrophy diet. Is there a diet which improves the...

5 answers

World map of Oculopharyngeal muscular dystrophy

Find people with Oculopharyngeal muscular dystrophy through the map. Connect with them and share experiences. Join the Oculopharyngeal muscular dystrophy community.

Stories of Oculopharyngeal muscular dystrophy

OCULOPHARYNGEAL MUSCULAR DYSTROPHY STORIES
Oculopharyngeal muscular dystrophy stories
Oculopharyngeal muscular dystrophy stories
My husband is 74 and was diagnosed with OPMD about 10 years ago.  He had a work related injury at the time and when they did some nerve testing they discovered it.  At that time he was experiencing some problems eating.  His mother had experienced...
Oculopharyngeal muscular dystrophy stories
I grow up with OPMD. My granddad suffered it and now my dad as well. I always lived with the fear to have it as I saw how bad this illness can affect the person. And now since several months I can say that I am also affected. It started already aroun...
Oculopharyngeal muscular dystrophy stories
Oculopharyngeal muscular dystrophy stories
Adopted, what a surprise OPMD was !!

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Oculopharyngeal muscular dystrophy forum

OCULOPHARYNGEAL MUSCULAR DYSTROPHY FORUM
Oculopharyngeal muscular dystrophy forum
I have read many articles about medical cannabis and Cannabis has the potential to help with the symptoms of muscular dystrophy in several ways. First off, the active compounds in marijuana are renowned for their ability to relieve inflammation and c...

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