Short answer · Medically reviewed summary · Last updated: 2026-05-08

Polycythemia Vera is classified under the ICD-10-CM code D45 and the ICD-9-CM code 238.4. These codes are essential for medical billing, clinical documentation, and tracking the prevalence of this myeloproliferative neoplasm within global health systems. What is the clinical significance of Polycythemia Vera coding? In medical practice, Polycythemia Vera is categorized as a chronic myeloproliferative neoplasm where the bone marrow produces too many red blood cells.

1 people with Polycythemia Vera have shared their first-person experience on this question at DiseaseMaps.

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ICD10 code of Polycythemia Vera and ICD9 code

ICD-10 and ICD-9 codes for Polycythemia Vera, with classification details for clinicians, coders and patients.

ICD9 and ICD10 codes of Polycythemia Vera

Polycythemia Vera is classified under the ICD-10-CM code D45 and the ICD-9-CM code 238.4. These codes are essential for medical billing, clinical documentation, and tracking the prevalence of this myeloproliferative neoplasm within global health systems.



What is the clinical significance of Polycythemia Vera coding?


In medical practice, Polycythemia Vera is categorized as a chronic myeloproliferative neoplasm where the bone marrow produces too many red blood cells. Using the correct ICD-10 code (D45) ensures that patients receive appropriate insurance coverage for specialized treatments, such as phlebotomy or cytoreductive therapy. Accurate coding is vital for researchers tracking the 118 members of our Polycythemia Vera community at DiseaseMaps.org who share their health journeys.



How is Polycythemia Vera classified in medical systems?


While ICD codes provide a framework for administrative data, clinicians differentiate Polycythemia Vera from secondary polycythemia based on the presence of the JAK2 mutation. Understanding these diagnostic codes helps physicians coordinate multidisciplinary care, which is crucial for managing the long-term risks associated with the disease.



What factors define the diagnosis of Polycythemia Vera?


The diagnosis is typically guided by the World Health Organization (WHO) criteria, which include specific laboratory markers and genetic testing. Key factors considered during the diagnostic process include:



  • Elevated Hemoglobin/Hematocrit levels: Often exceeding 16.5 g/dL in men or 16.0 g/dL in women.

  • JAK2 Mutation: Detected in approximately 95% of patients with Polycythemia Vera.

  • Bone Marrow Biopsy: Showing hypercellularity and panmyelosis.

  • Serum Erythropoietin Levels: Usually subnormal in cases of Polycythemia Vera.



Next steps



  • Consult with a hematologist or an MPN (myeloproliferative neoplasm) specialist to review your diagnostic records and ICD-10 documentation.

  • Connect with the 118 members of the DiseaseMaps.org Polycythemia Vera community to share experiences and coping strategies.

  • Keep a personal health file containing your latest CBC results and genetic testing reports to ensure your medical history remains accurate.



Medical disclaimer: This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment; always seek the advice of your physician regarding any medical condition.



References



  • National Institutes of Health (NIH) GARD: Polycythemia Vera.

  • Orphanet (ORPHA:733): Polycythemia vera.

  • OMIM (Online Mendelian Inheritance in Man): Entry #263300.

  • MPN Research Foundation: Understanding MPN diagnosis and coding.

Author: DiseaseMaps Editorial Team
Reviewed against authoritative medical sources (NIH GARD, Orphanet, OMIM)
Last updated: 2026-05-08
Medical disclaimer: This information does not substitute professional medical advice. Always consult your doctor before making health decisions.
Source: DiseaseMaps.org
2 answers
238.4 D45

Posted Sep 16, 2017 by Patricia 2000

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