Short answer · Medically reviewed summary · Last updated: 2026-05-08

Prolactinoma is classified under ICD-10 code D35.2 (Benign neoplasm of pituitary gland) and ICD-9 code 227.3 (Benign neoplasm of pituitary gland and craniopharyngeal duct). These codes are used by healthcare providers and insurance companies to specifically identify and process claims for this type of prolactin-secreting pituitary tumor. What exactly is a Prolactinoma? A Prolactinoma is the most common type of pituitary adenoma, accounting for approximately 30-40% of all pituitary tumors.

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ICD10 code of Prolactinoma and ICD9 code

ICD-10 and ICD-9 codes for Prolactinoma, with classification details for clinicians, coders and patients.

ICD9 and ICD10 codes of Prolactinoma

Prolactinoma is classified under ICD-10 code D35.2 (Benign neoplasm of pituitary gland) and ICD-9 code 227.3 (Benign neoplasm of pituitary gland and craniopharyngeal duct). These codes are used by healthcare providers and insurance companies to specifically identify and process claims for this type of prolactin-secreting pituitary tumor.



What exactly is a Prolactinoma?


A Prolactinoma is the most common type of pituitary adenoma, accounting for approximately 30-40% of all pituitary tumors. It is a non-cancerous growth that causes the pituitary gland to produce excessive amounts of the hormone prolactin, leading to hyperprolactinemia. Currently, 58 members in our DiseaseMaps community are managing their journey with a Prolactinoma, highlighting that while it is a rare diagnosis, you are not alone in navigating this endocrine condition.



How is a Prolactinoma clinically classified?


Clinicians generally categorize a Prolactinoma based on its size, which dictates the severity of symptoms and the chosen treatment pathway:



  • Microprolactinoma: Tumors smaller than 10 millimeters in diameter.

  • Macroprolactinoma: Tumors 10 millimeters or larger, which are more likely to cause mass-effect symptoms like headaches or vision changes.



How is a Prolactinoma diagnosed and treated?


Diagnosis typically involves blood tests to measure serum prolactin levels and an MRI of the sella turcica to visualize the tumor. Because Prolactinoma management is highly effective, most patients do not require surgery. First-line therapy usually consists of dopamine agonists, such as cabergoline or bromocriptine, which effectively shrink the Prolactinoma and normalize hormone levels in the vast majority of patients.



Next steps



  • Consult an endocrinologist to monitor your prolactin levels and tumor size regularly.

  • Join the DiseaseMaps community to connect with others who have been diagnosed with a Prolactinoma.

  • Keep a symptom diary to track side effects of medications or potential mass-effect symptoms like vision disturbances.



Medical disclaimer: This information is for educational purposes only and should not replace professional medical advice, diagnosis, or treatment from your healthcare provider.



References



  • National Institutes of Health (NIH) GARD: Prolactinoma overview.

  • Orphanet: Rare endocrine disease database (ORPHA:99908).

  • Pituitary Society: Clinical guidelines for the management of pituitary adenomas.

  • OMIM (Online Mendelian Inheritance in Man): Entry #176450 (Pituitary Adenoma).

Author: DiseaseMaps Editorial Team
Reviewed against authoritative medical sources (NIH GARD, Orphanet, OMIM)
Last updated: 2026-05-08
Medical disclaimer: This information does not substitute professional medical advice. Always consult your doctor before making health decisions.
Source: DiseaseMaps.org
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