Short answer · Medically reviewed summary · Last updated: 2026-04-06

There is no single "Scleroderma diet" that cures the condition, but specific dietary modifications are highly recommended to manage the gastrointestinal (GI) symptoms that affect up to 90% of people living with Scleroderma. Managing Gastrointestinal Symptoms Because Scleroderma can cause esophageal dysmotility, acid reflux, and small intestinal bacterial overgrowth (SIBO), the primary goal of nutrition is to improve digestion and comfort. Clinical experience suggests that eating smaller, more frequent meals rather than three large ones can significantly reduce the pressure on the lower esophageal sphincter, helping to manage the reflux often associated with Scleroderma. Recommended Dietary Adjustments Anti-Reflux Strategy: Avoid trigger foods like caffeine, alcohol, peppermint, chocolate, and spicy foods, which may relax the esophageal sphincter and exacerbate heartburn. Managing Malabsorption: If Scleroderma leads to SIBO or malabsorption, a low-FODMAP diet—supervised by a registered dietitian—may help reduce bloating and abdominal discomfort. Hydration: Staying well-hydrated is essential, especially if skin thickening or joint involvement makes physical activity challenging.

13 people with Scleroderma have shared their first-person experience on this question at DiseaseMaps.

5

Scleroderma diet. Is there a diet which improves the quality of life of people with Scleroderma?

Diet and Scleroderma: foods that patients report help their quality of life, with a medically reviewed summary.

Scleroderma diet

There is no single "Scleroderma diet" that cures the condition, but specific dietary modifications are highly recommended to manage the gastrointestinal (GI) symptoms that affect up to 90% of people living with Scleroderma.



Managing Gastrointestinal Symptoms


Because Scleroderma can cause esophageal dysmotility, acid reflux, and small intestinal bacterial overgrowth (SIBO), the primary goal of nutrition is to improve digestion and comfort. Clinical experience suggests that eating smaller, more frequent meals rather than three large ones can significantly reduce the pressure on the lower esophageal sphincter, helping to manage the reflux often associated with Scleroderma.



Recommended Dietary Adjustments



  • Anti-Reflux Strategy: Avoid trigger foods like caffeine, alcohol, peppermint, chocolate, and spicy foods, which may relax the esophageal sphincter and exacerbate heartburn.

  • Managing Malabsorption: If Scleroderma leads to SIBO or malabsorption, a low-FODMAP diet—supervised by a registered dietitian—may help reduce bloating and abdominal discomfort.

  • Hydration: Staying well-hydrated is essential, especially if skin thickening or joint involvement makes physical activity challenging. Sip water throughout the day rather than drinking large amounts during meals, as this can improve digestion.



Supplements and Medications


Evidence regarding supplements for Scleroderma remains limited. Some patients may require Vitamin B12, iron, or Vitamin D supplementation if their GI tract is not absorbing nutrients efficiently. Always consult your rheumatologist before starting supplements, as they can interact with medications like immunosuppressants or proton pump inhibitors (PPIs) used to manage Scleroderma symptoms.



Evidence-Based Perspective


While diets such as the ketogenic or strictly elimination diets are often discussed in online forums, there is currently no high-level clinical evidence supporting them as a treatment for Scleroderma. Nutritional focus should remain on a balanced, anti-inflammatory approach tailored to your specific GI symptoms. Always track your intake and symptoms in a food diary to discuss with your healthcare team, as this provides the most accurate data for your personalized care plan.



Medical Disclaimer: This information is for educational purposes and does not replace professional medical advice. Always consult with your rheumatologist or a registered dietitian specializing in autoimmune conditions before making significant changes to your diet or supplement regimen.



References



  • NIH Genetic and Rare Diseases Information Center (GARD)

  • Scleroderma Foundation (Diet and Nutrition Resources)

  • Orphanet (Systemic Sclerosis clinical guidelines)

Author: DiseaseMaps Editorial Team
Reviewed against authoritative medical sources (NIH GARD, Orphanet, OMIM)
Last updated: 2026-04-06
Sources cited: NIH Genetic and Rare Diseases Information Center (GARD) · Scleroderma Foundation (Diet and Nutrition Resources) · Orphanet (Systemic Sclerosis clinical guidelines)
Medical disclaimer: This information does not substitute professional medical advice. Always consult your doctor before making health decisions.
Source: DiseaseMaps.org
14 answers
Avoid oily and fatty food as they cause heartburns. Moreover use as many greens as you can and stick to fresh food.

Posted Apr 1, 2017 by Fashah 1150
I avoid gluten and also red meat. Also coffee.
Try to eat organic fruit and vegetables. Drink lots of water.

Posted Apr 1, 2017 by Milda 1000
While it is certainly the case that because of GI problems such as chronic heartburn, difficulty swallowing, etc., dietary changes to minimize these symptoms are very important, there is no research that suggests that diets have any systemic effects in systemic scleroderma. Fads like gluten free are only relevant for the very small portion of patients with celiac disease or true gluten sensitivity, but this will not alter the overall course of the disease.

Posted Apr 4, 2017 by Choclit 1150
Some say Gluten free diets work well with all of the stomach issues Scleroderma patients tend to have.!i try to stay away from acidic foods, any thing with tomatoes, fried foods, caffeine and I try not to eat too late at night.

Posted Mar 30, 2018 by Amy 2600
Yes, I believe a good diet can improve Scleroderma. However, no diet is an answer to all of those who suffer from Scleroderma. The Mediterannean diet might be helpful. For me, low fat, lots of vegetable, some fruits, and reduced red meat and elimination of sodas helped. No fatty foods before 7:00 or at the last meal of the day. No high sugar intake at bedtime or before 7:00 pm is helpful. Actually, eliminate big meals, smaller (and more) meals is better for anyone. This will improve the quality of life for anyone.

Posted Nov 21, 2018 by Juanita 1900
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Avoid cafeinas flours gluten

Posted Feb 24, 2017 by 1000
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there is not great evidence, but it is recommended a gluten-free diet must avoid caffeine, alcohol, and in general the irritants by gastroesophageal reflux.

Posted Feb 27, 2017 by cecilia miranda 1000
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I don't think there is anything concrete. It would make the diet healthy and balanced.

Posted Mar 21, 2017 by Amparo 1000
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All those foods that contain. Collagen should be avoided such as eggs, gelatine, containing vitamin C diet low in cholesterol is very good, the white meat olive oil, and nuts

Posted Mar 23, 2017 by ana h 1400
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Rarely. Foods to avoid: pork meat, fats, coffee, acids, beans.

Posted Apr 28, 2017 by Alma Olivia 1000
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We need to eat a balanced diet and possibilities, also will influence the capacity that we have to swallow the food because the scleroderma affects the esophagus and narrow and not be able to swallow certain types of foods for being very mushy and the other situation is that because of the medication you may be taking can have ailments of stomach

Posted May 15, 2017 by Lucero 1050
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Normally the doctors do not give much information on the topic of the power but by my experience I think that is important because I have noticed changes to stop taking certain foods. The gluten x example should be avoided in auto immune diseases such as scleroderma. It has also helped me a lot not to take dairy or sugar, preventing heartburn, and mucus. If there are problems of reflux tb it is important to eat dinner early and do not eat very fatty foods or fried foods, tomato and peppers. Drink a lot of water but always between meals, don't drink when we're eating.

Posted May 18, 2017 by Montse 1151
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I believe that a diet based on the fall of the inflammation.
Any kind of food that fight inflammation in the body.

Posted Sep 30, 2017 by Carol 1000

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