Short answer · Medically reviewed summary · Last updated: 2026-05-08
Secondary Haemochromatosis is classified under ICD-10 code E83.119 (Hereditary hemochromatosis, unspecified, though often coded as secondary iron overload under E83.110 or E83.118 depending on the cause) and ICD-9 code 275.09. Unlike primary (hereditary) forms, Secondary Haemochromatosis results from iron overload caused by external factors such as chronic blood transfusions, ineffective erythropoiesis, or excessive iron intake. What distinguishes Secondary Haemochromatosis from primary forms? While primary haemochromatosis is caused by genetic mutations (most commonly in the HFE gene), Secondary Haemochromatosis is an acquired condition.
ICD10 code of Secondary Haemochromatosis and ICD9 code
ICD-10 and ICD-9 codes for Secondary Haemochromatosis, with classification details for clinicians, coders and patients.
Secondary Haemochromatosis is classified under ICD-10 code E83.119 (Hereditary hemochromatosis, unspecified, though often coded as secondary iron overload under E83.110 or E83.118 depending on the cause) and ICD-9 code 275.09. Unlike primary (hereditary) forms, Secondary Haemochromatosis results from iron overload caused by external factors such as chronic blood transfusions, ineffective erythropoiesis, or excessive iron intake.
What distinguishes Secondary Haemochromatosis from primary forms?
While primary haemochromatosis is caused by genetic mutations (most commonly in the HFE gene), Secondary Haemochromatosis is an acquired condition. The iron overload in Secondary Haemochromatosis typically occurs because the body receives more iron than it can store or utilize, often due to medical treatments rather than a metabolic defect. Understanding this distinction is vital for clinical management and patient peace of mind.
What are the common causes of iron overload?
Secondary Haemochromatosis is frequently associated with conditions requiring chronic medical intervention. Common triggers include:
- Chronic blood transfusions for conditions like thalassemia or sickle cell disease.
- Ineffective erythropoiesis, where the body produces red blood cells that fail to mature.
- Chronic liver disease, such as hepatitis C or alcoholic liver disease, which can impair iron metabolism.
- Long-term excessive iron supplementation or dietary intake.
How is Secondary Haemochromatosis diagnosed?
Diagnosis of Secondary Haemochromatosis involves monitoring iron markers, specifically serum ferritin levels and transferrin saturation. Physicians often use MRI (R2* or T2* sequences) to quantify iron deposition in the liver and heart. Because Secondary Haemochromatosis can lead to organ damage if left untreated, early detection through regular blood panels is essential for those at risk.
Is there support for those living with this condition?
Living with Secondary Haemochromatosis can feel isolating, but you are not alone. Currently, 3 members of the DiseaseMaps.org community are managing Secondary Haemochromatosis and sharing their lived experiences. Connecting with others can provide emotional support and practical strategies for managing the fatigue and organ-specific symptoms often associated with iron overload.
Next steps
- Consult a hematologist or hepatologist to discuss iron chelation therapy if your ferritin levels are elevated.
- Request a referral for a cardiac MRI if you have been receiving chronic transfusions.
- Join the DiseaseMaps.org community to connect with other members navigating the realities of Secondary Haemochromatosis.
Medical disclaimer: This information is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment.
References
- NIH Genetic and Rare Diseases Information Center (GARD) - Iron Overload Disorders.
- Orphanet: Rare Disease Database (ORPHA: 387).
- World Health Organization (WHO) ICD-10 Browser (E83.1).
- OMIM (Online Mendelian Inheritance in Man) - Iron Metabolism Disorders.
