In my opinion, while the group of Ottawa does not publish its results at 5 years, the most accessible are the immunosuppressants, which have more experience is the Rituximab, But the valium, rivotril no time disappear from the scene. It is what is called compassionate treatment. Same is the case with Sativex (a component in marijuana), which can decrease spasticity.
We have neglected the treatment with corticosteroids (contrindicado in diabetics), the IVgA unspecific and plasmapheresis for being a little useful.