Short answer · Medically reviewed summary · Last updated: 2026-04-07

Acanthamoeba keratitis is classified under the ICD-10 code H16.03 (Acanthamoeba keratitis) and the ICD-9 code 370.04 (Acanthamoeba keratitis). These codes are used by healthcare providers and insurance systems to specifically identify this rare, sight-threatening parasitic infection of the cornea. What is Acanthamoeba keratitis and why is classification important? Acanthamoeba keratitis is a rare, severe infection of the cornea caused by the Acanthamoeba organism, a free-living amoeba commonly found in water sources like tap water, swimming pools, and hot tubs.

1 people with Acanthamoeba keratitis have shared their first-person experience on this question at DiseaseMaps.

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ICD10 code of Acanthamoeba keratitis and ICD9 code

ICD-10 and ICD-9 codes for Acanthamoeba keratitis, with classification details for clinicians, coders and patients.

ICD9 and ICD10 codes of Acanthamoeba keratitis

Acanthamoeba keratitis is classified under the ICD-10 code H16.03 (Acanthamoeba keratitis) and the ICD-9 code 370.04 (Acanthamoeba keratitis). These codes are used by healthcare providers and insurance systems to specifically identify this rare, sight-threatening parasitic infection of the cornea.



What is Acanthamoeba keratitis and why is classification important?


Acanthamoeba keratitis is a rare, severe infection of the cornea caused by the Acanthamoeba organism, a free-living amoeba commonly found in water sources like tap water, swimming pools, and hot tubs. Because this condition is frequently misdiagnosed as other forms of keratitis, accurate medical coding via the ICD-10 and ICD-9 systems is essential for tracking incidence and ensuring appropriate insurance coverage for intensive, long-term treatment. Currently, 197 people with Acanthamoeba keratitis have joined the DiseaseMaps community, highlighting the importance of shared experiences in navigating the diagnostic journey for this rare condition.



How is Acanthamoeba keratitis diagnosed?


Diagnosis of Acanthamoeba keratitis is often challenging because the symptoms—which include severe ocular pain, light sensitivity, and blurred vision—mimic common bacterial or viral infections. Because standard eye drops often fail to resolve the infection, clinical suspicion is key. Diagnosis typically involves the following steps:



  • Corneal Scraping: A specialist obtains a sample of the infected corneal tissue for culture and microscopic examination.

  • In Vivo Confocal Microscopy (IVCM): A non-invasive imaging technique that allows ophthalmologists to visualize the cysts of Acanthamoeba within the corneal layers in real-time.

  • Polymerase Chain Reaction (PCR): Highly sensitive molecular testing used to detect the DNA of the organism even when culture results are negative.



What are the risk factors for developing Acanthamoeba keratitis?


While Acanthamoeba keratitis can affect anyone, the vast majority of cases are linked to contact lens wear. Poor contact lens hygiene—such as using tap water to rinse lenses, swimming while wearing lenses, or topping off lens solution—significantly increases the risk of exposure. Although rare, non-contact lens wearers can also develop Acanthamoeba keratitis following ocular trauma involving contaminated soil or water. Early recognition of these risks is vital, as the parasite is notoriously difficult to eradicate once it penetrates the deeper layers of the cornea.



How is the emotional impact of Acanthamoeba keratitis managed?


Living with Acanthamoeba keratitis can be incredibly isolating due to the intense pain and the long duration of treatment, which can sometimes last for months or even years. The clinical psychologist team at DiseaseMaps emphasizes that the uncertainty regarding visual recovery often leads to significant anxiety. Connecting with others who have navigated the treatment protocols for Acanthamoeba keratitis can provide a crucial sense of validation and hope during the recovery process.



Next steps



  • Consult a cornea specialist or ophthalmologist immediately if you experience persistent eye pain or light sensitivity while wearing contact lenses.

  • Join the 197 members of the DiseaseMaps community for Acanthamoeba keratitis to share experiences and coping strategies.

  • Ensure your medical records accurately reflect the diagnosis using the correct ICD-10 code (H16.03) to assist in coordinated care.

  • Strictly adhere to your prescribed topical antimicrobial regimen, as treatment for Acanthamoeba keratitis requires high compliance to prevent recurrence.



Medical disclaimer: This information is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment; always seek the advice of your physician regarding any medical condition.



References



  • NIH Genetic and Rare Diseases Information Center (GARD): Acanthamoeba keratitis overview.

  • Orphanet: Rare eye disease database (ORPHA:99955).

  • Centers for Disease Control and Prevention (CDC): Acanthamoeba keratitis prevention and clinical information.

  • American Academy of Ophthalmology (AAO): Clinical guidelines for the management of corneal infections.

Author: DiseaseMaps Editorial Team
Reviewed against authoritative medical sources (NIH GARD, Orphanet, OMIM)
Last updated: 2026-04-07
Medical disclaimer: This information does not substitute professional medical advice. Always consult your doctor before making health decisions.
Source: DiseaseMaps.org
2 answers
ICD -10 - CM B60.13 became effective on 1 October 2018
In the UK these codes are not needed as treatment is covered by The National Health Service

Posted Feb 24, 2019 by Liz Crane 2510

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Sono 6 mesi che lotto contro l'http://www.acanthamoeba.org/ e ancora non ne sono uscito. Sto assumendo PHMB e cortisone e speriamo di guarire al piu' presto

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Acanthamoeba keratitis forum

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Dear acanthamoeba keratitis friends, My question: can you tell me the name and adress of your hospital where you are threated? My explantion: Unfortunately I'm diagnosed with AK for 2 months now. Now this is the thing: I'm going to make a wo...
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