Short answer · Medically reviewed summary · Last updated: 2023-07-13

Acanthosis Nigricans is a skin condition characterized by dark, thickened patches of skin that typically appear in the folds and creases of the body. These patches usually have a velvety texture and can range in color from light brown to black.

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What is Acanthosis Nigricans

What is Acanthosis Nigricans? Plain-language, medically reviewed definition plus the lived reality told by patients.

What is Acanthosis Nigricans

Acanthosis Nigricans is a skin condition characterized by dark, thickened patches of skin that typically appear in the folds and creases of the body. These patches usually have a velvety texture and can range in color from light brown to black. Acanthosis Nigricans is often a sign of an underlying health issue, such as obesity, insulin resistance, or hormonal disorders.


The condition is most commonly found in areas such as the neck, armpits, groin, and skin folds. It can also affect the lips, palms, and soles of the feet. While Acanthosis Nigricans itself is harmless and painless, it is important to address the underlying cause.


Obesity is a significant risk factor for developing Acanthosis Nigricans, as excess weight can lead to insulin resistance. Insulin resistance occurs when the body's cells do not respond properly to insulin, resulting in elevated blood sugar levels. Hormonal disorders, such as polycystic ovary syndrome (PCOS), can also contribute to the development of Acanthosis Nigricans.


If you notice dark, thickened patches of skin on your body, it is advisable to consult a healthcare professional for an accurate diagnosis and appropriate treatment options.


Author: DiseaseMaps Editorial Team
Reviewed against authoritative medical sources (NIH GARD, Orphanet, OMIM)
Last updated: 2023-07-13
Medical disclaimer: This information does not substitute professional medical advice. Always consult your doctor before making health decisions.
Source: DiseaseMaps.org
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