In the united States, the National Institute of Neurological Diseases (NINDS), dependent of the National Institute of Health (NIH), is conducting several studies and research on Chiari malformation. These works are carried out in the laboratories of the NIH located in Bethesda, Maryland.
The research consists of:
Efforts to identify the genes responsible for the malformation, investigating subjects with Chiari who have a family member affected with the same disease or syringomyelia.
The search for surgical methods with alternative non-invasive to the syringomyelia, which consist in attaining to correct the abnormal flow of CSF without cutting the cord itself.
Comparison between the prenatal surgery of myelomeningocele and conventional methods postnatal. Participating in this study 200 pregnant women whose fetuses have spina bifida. Some children will be operated in uterus and other as per the usual procedure. The clinical evidence preliminary suggests that surgical closure of an intrauterine of the myelomeningoceles drastically reduces the dependence of valves after the birth, and that restores the cerebellum and brainstem to configurations much more normal.6 children operated will be evaluated and compared to one year and two and a half years after the operation to verify the motor function, the evolutionary progress and the development of bladder, kidneys, and brain.