Short answer · Medically reviewed summary · Last updated: 2023-07-13
Coloboma is a rare congenital eye abnormality characterized by a missing piece of tissue in one or more structures of the eye, such as the iris, retina, choroid, or optic disc. This condition can affect one or both eyes and may vary in severity. While coloboma is considered a rare condition, its exact prevalence is not well-established due to variations in reporting and diagnosis.
What is the prevalence of Coloboma?
Prevalence of Coloboma: how many people are affected worldwide, differences by sex and region, with sources.
Coloboma is a rare congenital eye abnormality characterized by a missing piece of tissue in one or more structures of the eye, such as the iris, retina, choroid, or optic disc. This condition can affect one or both eyes and may vary in severity.
While coloboma is considered a rare condition, its exact prevalence is not well-established due to variations in reporting and diagnosis. However, studies suggest that the estimated prevalence of coloboma ranges from 1 in 10,000 to 1 in 20,000 live births.
Coloboma can occur as an isolated condition or as part of a genetic syndrome. It may be inherited in an autosomal dominant, autosomal recessive, or X-linked manner, or it can occur sporadically without a family history. The underlying cause of coloboma is often related to abnormal development during embryogenesis.
Individuals with coloboma may experience visual impairment or other associated eye problems, such as nystagmus, strabismus, or refractive errors. Treatment options depend on the specific structures affected and the severity of the condition, and may include corrective lenses, surgery, or vision aids.
