Short answer · Medically reviewed summary · Last updated: 2023-07-13
Critical limb ischemia (CLI) is a severe form of peripheral arterial disease (PAD) that results in inadequate blood flow to the lower extremities. It is characterized by chronic ischemic rest pain, non-healing wounds, and tissue loss, which can ultimately lead to limb amputation if left untreated.
What is the prevalence of Critical limb ischemia?
Prevalence of Critical limb ischemia: how many people are affected worldwide, differences by sex and region, with sources.
Critical limb ischemia (CLI) is a severe form of peripheral arterial disease (PAD) that results in inadequate blood flow to the lower extremities. It is characterized by chronic ischemic rest pain, non-healing wounds, and tissue loss, which can ultimately lead to limb amputation if left untreated. CLI primarily affects individuals with advanced age, diabetes, smoking history, and other cardiovascular risk factors.
Estimating the exact prevalence of CLI can be challenging due to variations in study populations and diagnostic criteria. However, it is generally recognized as a relatively rare condition. Studies suggest that the prevalence of CLI ranges from 500 to 1000 cases per million population. The incidence of CLI increases with age, with a higher prevalence observed in individuals over 60 years old.
CLI poses a significant burden on healthcare systems and patients alike. It is associated with substantial morbidity, mortality, and reduced quality of life. Early diagnosis and appropriate management are crucial in preventing disease progression and improving outcomes for individuals with CLI.
